NTHAWI YAULERE YAULERE

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Thupi labwinobwino
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Kuwonongeka kwa mpweya
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Ultraviolet ma radiation
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Kuwononga kwakukulu kwazitsulo
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Kuwononga mankhwala ophera tizilombo
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Kuwononga mankhwala ophera tizilombo

 

 

ZOCHITIKA ZAULERE NDI MATENDA

 

Nthawi zambiri, kusintha kwaulere kumafunikira mthupi, koma kusintha mopitilira muyeso kumatha kuyambitsa kusakhazikika kwa magwiridwe antchito, kenako kumabweretsa kupsinjika kwa oxidative komwe kumatulukira m'matenda osiyanasiyana (zolemba zimawonetsa kuti zopitilira muyeso ndiye gwero la matenda osiyanasiyana).

 

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WOSANGALATSA

 

Thupi lathu silingagwire ntchito popanda oxygen, ndipo kuchuluka kwa zopitilira muyeso kwaulere zikawonjezeka, thupi lomwe lili ndi kupsinjika kwa oxidative limapangitsa kuti kukonza kukhale kolephera kuchotsa zopitilira muyeso zaulere. Nthawi yapadera, thupi limafunikira kuti likhale ndi ma antioxidants mu vitro kuti lichotse zopitilira muyeso zaulere.

 

KUKONZETSA KWA ANTIOXIDANTS

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L-ERGOTHIONEINE -Mtundu watsopano wa mankhwala achilengedwe

 

CHIKHALA Ndi chiral wachilengedwe amino-acid antioxidant biosynthesized m'mabakiteriya ena ndi bowa. Ndi gawo lofunikira la bioactive lomwe lakhala likugwiritsidwa ntchito ngati chowotcha chopitilira muyeso, fyuluta ya ray ya ultraviolet, yowongolera mayikidwe ochepetsa makutidwe ndi okosijeni ndi ma cell a bioenergetics, ndi cytoprotector ya thupi, ndi zina zambiri.
L-Ergothioneine (EGT, ERGO, CAS: 497-30-3), wotchedwanso (S) -cy-Carboxy-2,3-dihydro-N, N, N-trimethyl-2-thioxo-1H-imidazole- Mchere wamkati wa 4-ethanaminium, unayamba kutulutsidwa kuchokera ku ergot ndi Tanret C mu 1909, ndiye kuti udapezekanso m'magazi amanyama. Pure EGT ndi kristalo woyera, sasungunuka m'madzi, (anasungunuka 0.9mol / L pa kutentha kwa firiji). Autoxidation siyingachitike mwakuthupi pH yamtengo wapatali kapena njira yamphamvu yamchere. EGT imatha kupezeka m'mitundu iwiri ya isomer - mawonekedwe a thiol ndi thione, monga akuwonekera pansipa:

 

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KUSINTHA

Ndi maubwino amitundu ingapo, CHIKHALA amadziwika pakati pa ma antioxidants ambiri.

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ubwino

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Ndi maubwino amitundu ingapo, EGT imadziwika pakati pa ena ambiri antioxidantsUbwino (poyerekeza ndi glutathione, cysteine ​​etc.):
——EGT ndiyosavuta kupezeka m'maselo ndipo ndende ndiyokhazikika kuposa ma antioxidants ena.
——EGT ndi yothandiza kwambiri pakuchepetsa kufa kwa maselo chifukwa cha pyrogallol.
-—EGT makamaka imalanda ROS kuti ipewe makutidwe ndi okosijeni, pomwe glutathione ndi ena amadzipweteka mopanda malire, ndiye kuti, ena antioxidants scavenge mankhwala okosijeni.(1) Oleoylethanolamide (oea) -amatsenga amatsenga amoyo wanu

CHIFUNDO CHA ANTIOXIDATION

Results: CHIKHALA anali mkangaziwisi wogwira ntchito mwamphamvu kwambiri poyerekeza ndi ma antioxidants akale monga GSH, uric acid ndi trolox. Makamaka, mphamvu yayikulu kwambiri yama antioxidant yowonetsedwa ndi EGT vs. peroxyl radicals idapangitsa 25% kukhala yayikulu kuposa mtengo womwe umapezeka ndi antioxidant trolox. Kutha kwa EGT kwa ma hydroxyl radicals kunali 60% kuposa, poyerekeza ndi uric acid, yomwe imayimira antioxidant vs. hydroxyl radicals. Pomaliza, EGT idawonetsanso antioxidant yomwe imagwiranso ntchito kwambiri ku peroxynitrite, yokhala ndi mphamvu zowononga 10% kuposa uric acid.

 

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ZINTHU ZINA

 

EGT imathandizanso kuwongolera mphamvu zamagetsi,

kukulitsa chitetezo chokwanira,

kukonza umuna,

Kuteteza chiwindi kuti chisavulazidwe,

kuletsa kutupa,

mitsempha,

Kukula kwazovuta komanso zowopsa.

 

 

ZOFUNIKA ZA KUKULA

G MAGANI AMAKHALANSO KWAMBIRI M'MALO NDI NYAMA

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② MALANGIZO

5-10mg Pagulu la munthu wamkulu ndipo mayunitsi awiri mwa magawo awiri ndikudya mosalekeza ndikofunikira pazakudya zanu za tsiku ndi tsiku.

Gwero: Li Yiqun, Zhou Nianbo. Ntchito za Biology ndi Ntchito za EGT [J]. Chakudya Chaukadaulo, 2010 chuma9 (3) : 26-28.

Zowonjezera zidalembedwa motere:

Ana (zaka 3-11) ≤l 0 mg / tsiku
Achinyamata (zaka 11 mpaka 21) ≤30 mg / tsiku
Akuluakulu (zaka 21-80) ≤30 mg / tsiku

Chidziwitso: 1. Mlingo wa ana ndi akulu (zaka 3 -80)

           2. Gwiritsani ntchito amayi apakati kapena oyamwitsa sikuvomerezeka.

Gwero lazambiri: Tetrahedron mukalembetsa ku US NDI

Zambiri zikusonyeza: 10.5mg / g ya OXIS's ADI (Yovomerezeka Tsiku Lililonse).

 

Y ZOCHITIKA

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KUCHITSA NDI KUGWIRITSA NTCHITO

(1) KUCHOTSA

Pakadali pano, pali njira zitatu zopangira EGT: kaphatikizidwe wamankhwala, achilengedwe bio-kuchotsa (makamaka kuchokera ku bowa, ziweto za nyama ndi kuchotsa magazi), ndi njira ya biosynthesis.

Kuyerekeza Kuchotsa kwa EGT Njira

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(2) NTCHITO

EGT imagwiritsa ntchito zodzoladzola, zakudya zogwira ntchito, mankhwala, mankhwala, biomedicine, ndi zina zotero.

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(3) MAFUNSO ENA OTHANDIZA

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Zothandizira

  1. Oleoylethanolamide (oea) -wotenga zamatsenga m'moyo wanu
  2. Anandamide vs cbd: ndi iti yomwe ili yabwinoko ku thanzi lanu? Chilichonse chomwe muyenera kudziwa za iwo!
  3. Chilichonse chomwe muyenera kudziwa za nicotinamide riboside chloride
  4. Mankhwala a magnesium l-threonate: maubwino, kuchuluka kwake, ndi zotsatirapo zake
  5. Palmitoylethanolamide (mtola): ubwino, mlingo, ntchito, zowonjezera
  6. Mapindu apamwamba 6 azaumoyo a resveratrol supplements
  7. Ubwino wapamwamba wa 5 wakumwa phosphatidylserine (ps)
  8. Maubwino apamwamba 5 otenga pyrroloquinoline quinone (pqq)
  9. Chithandizo chabwino kwambiri cha alpha gpc
  10. Chithandizo chabwino kwambiri chotsutsana ndi kukalamba cha nicotinamide mononucleotide (nmn)

 

Nkhani ndi: Dr. Zeng

Nkhani ndi:

Dr. Zeng

Co-founder, utsogoleri waukulu wa kampani; PhD inalandira kuchokera ku Yunivesite ya Fudan mu organic chemistry. Zoposa zaka zisanu ndi zinayi zokumana nazo zamagulu azipangidwe zamagetsi ndi kapangidwe ka mankhwala; pafupifupi mapepala ofufuza 10 omwe adasindikizidwa m'magazini odalirika, okhala ndi ma patenti opitilira asanu aku China.

 

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