Chithandizo Chabwino Kwambiri Chotsutsana ndi Kukalamba cha Nicotinamide Mononucleotide (NMN)

Pambuyo pa kafukufuku wa 2019 adamaliza Nicotinamide Mononucleotide ndiyabwino kuti anthu azigwiritsa ntchito ngati mowa umangokhala malire, makampani angapo opanga zinthu alowa mumsika ndi zopereka zawo. Kuchuluka kwa zisankhozi kwasiya ogula akusokonezedwa Nictonimade Mononucleotide (NMN) chowonjezera ndibwino kwa iwo. M'malingaliro athu, chowonjezera chabwino chotsutsa ukalamba cha Nicotinamide Mononucleotide (NMN) mu 2021 ndi kampani ya Cofttek.
Cofttek ndi kampani yovoteledwa ndi A + yomwe yakhala ili pamsika kwa zaka pafupifupi 12 ndipo yakhala ikutsatira mokhulupirika panthawiyi. Powder ya NMN yoperekedwa ndi kampaniyo imayesedwa katatu labu, NMN yopanga mankhwala yochokera kumakampani omwewo omwe adapereka NMN pamayeso osiyanasiyana azachipatala omwe adachitika pazaka zambiri. Pulogalamu ya Ufa wa NMN choperekedwa ndi Cofttek chimathandizira kuloza kwake kosavuta kulowa mthupi, potero kumawonjezera kuchuluka kwazomwe zimapangidwira komanso ntchito zake zolimbitsa thupi. Chofunika kwambiri, ufa uwu umabwera mochuluka ndipo mutha kuwusunga kwa miyezi itatu. Zonse, izi ndi chimodzi mwazinthu zabwino zowonjezera zomwe zimapezeka pamsika zomwe zili ndi ogwiritsa ntchito ambiri ndipo zimachokera ku kampani yomwe yakhala ikutulutsa zinthu zodalirika komanso zothandiza chaka ndi chaka.

Kodi Nicotinamide Mononucleotide (NMN) ndi chiyani?

Nicotinamide Mononucleotide (1094-61-7) kapena NMN ndi nucleotide yomwe imakhalapo mwachilengedwe mwa zakudya zambiri zomwe timadya. Amapezeka mu avocado, broccoli, nkhaka, kabichi, edamame, ndi tomato. Komabe, kuchuluka kwa NMN komwe kumaperekedwa ndi zakudya izi sikokwanira kukwaniritsa magwiridwe antchito amthupi ndipo chifukwa chake, anthu amalangizidwa kuti atenge zowonjezera za NMN. Koma, ndichifukwa chiyani NMN ili yofunikira kwambiri mthupi?

Nicotinamide Mononucleotide kapena NMN ndiyotsogola kwa Nicotinamide Adenine Dinucleotide kapena NAD +. M'mawu osavuta, NMN ndiye gulu lomwe limasandulika kukhala NAD + kudzera munthawi zosiyanasiyana zomwe zimachitika mkati mwa maselo. NAD +, mbali ina, imawerengedwa kuti ndi yofunika kwambiri m'thupi chifukwa imagwira ntchito zingapo zofunika, kuphatikiza kusinthasintha kwa thupi, kuswa michere kuti ipatse mphamvu zamagetsi, komanso kuthandizira kusintha kwa michere, komwe kumachedwetsa kukalamba. Tsoka ilo, ngakhale NAD + imapezeka mkati mwa selo iliyonse ya thupi, kupanga kwake kumachepa ndi msinkhu. Chofunika kwambiri, palibe zakudya zomwe munthu angadye kuti achulukitse kupanga NAD + m'thupi. Chifukwa chake, thupi limafuna chithunzithunzi cha NAD + chomwe chimasandulika NAD + mkati mwa selo, potero chimapangitsa kutsika kwake mthupi. Apa ndipomwe kugwiritsa ntchito zowonjezera za NMN kumayamba.

Kodi Nmn ndi yabwino bwanji?

NMN yapezeka ikuthandizira kuchita ntchito ya insulin komanso kupanga, zomwe zimapangitsa phindu lina la kagayidwe kachakudya komanso kulolerana kwa shuga. Makamaka, zowonjezera za NMN zitha kuthandiza kuti muchepetse kagayidwe kachakudya monga matenda ashuga, matenda a chiwindi, ndi kunenepa kwambiri.

Kodi Nmn angasinthe ukalamba?

Utsogoleri wa nicotinamide mononucleotide (NMN) akuwonetsedwa kuti athetse zovuta zokhudzana ndi ukalamba.Nicotinamide mononucleotide (NMN) supplementation imalimbikitsa kuthana ndi ukalamba miRNA expression profile mu aorta ya mbewa zakale, kulosera za epigenetic kukonzanso ndi anti-atherogenic zotsatira.

Mumakulitsa bwanji Nmn mwachilengedwe?

NMN itha kuperekedwa mosamala kwa mbewa ndipo imapezeka mwachilengedwe muzakudya zingapo, kuphatikiza broccoli, kabichi, nkhaka, edamame ndi peyala. Kafukufuku watsopanoyu akuwonetsa kuti NMN ikasungunuka m'madzi akumwa ndikupatsidwa mbewa, imawoneka m'magazi pasanathe mphindi zitatu.

Kodi Nmn ingakulitse moyo wautali?

Asayansi aphunzira magawo awiri oterewa, nicotinamide riboside (NR) ndi nicotinamide mononucleotide (NMN), kwambiri kuposa ena, ndipo kafukufukuyu amalimbikitsa. Kafukufuku angapo akuwonetsa kuti kuwonjezera pazomwe zidachitikazi kumatha kukulitsa milingo ya NAD + ndikuchulukitsa moyo wa yisiti, mphutsi, ndi mbewa.

Kodi Nmn amakhala nthawi yayitali bwanji m'dongosolo lanu?

Kafukufuku wathu wapano akuwonetseratu kuti NMN imayamwa mwachangu m'matumbo ndikuyenda magazi mkati mwa 2-3 min ndikuchotsedwanso magazi kuchokera kumatumba mkati mwa 15 min.

Kodi chimachitika ndi chiyani mukasiya kutenga Nmn?

Resveratol ndi NMN onse amagwira ntchito pokonzanso kuthekera kwa maselo mthupi lanu kuti adzikonze. Chifukwa chake, ngati mungawatenge kwakanthawi ndikuyiyimitsa sikungapangitse kuti mubwerere pomwe mudali momwemo musanazitenge chifukwa zosinthazo ndizomwe zimapangitsa kusintha kwama cell.

Kodi Nmn imakupangitsa kuti uwoneke wachichepere?

"Labu yathu yawonetsa kuti kupereka mbewa kwa NMN kwa miyezi yopitilira 12 kukuwonetsa zotsatira zabwino zotsutsana ndi ukalamba." Malinga ndi Imai, kutanthauzira zotsatirazi kwa anthu kukuwonetsa kuti NMN ikhoza kupatsa munthu kagayidwe kazaka zazaka 10 mpaka 20.

Kodi chowonjezera chabwino kwambiri pakhungu lokalamba ndi chiyani?

Zowonjezera 12 Zabwino Kwambiri Zotsutsana ndi Kukalamba

• Curcumin
• EGCG
• Collagen
• CoQ10
• Nicotinamide riboside ndi nicotinamide mononucleotide
• Ng'ona
• theanini
• Rhodiola
• Adyo
• Astragalus
• Fisetin
• Resveratrol

Kodi ndingasinthe bwanji makwinya mwachilengedwe?

• Valani dzuwa.
• Chepetsani kudya shuga.
• Siyani kusuta.
• Gwiritsani kokonati mafuta.
• Tengani beta carotene.
• Imwani tiyi wa masamba a mandimu.
• Sinthani malo ogona.
• Sambani nkhope yanu.
• Pewani kuwala kwa ultraviolet
• Sinthani ma antioxidants anu

Kodi ndingasinthe bwanji khungu lokalamba?

Pofuna kuthandiza odwala awo kupewa kukalamba msanga, dermatologists amapatsa odwala malangizo otsatirawa.

• Tetezani khungu lanu padzuwa tsiku lililonse.
• Ikani chofufuta nsalu m'malo mozipeza.
• Ngati mumasuta, siyani.
• Pewani kubwereza nkhope.
• Idyani chakudya chopatsa thanzi, chopatsa thanzi.
• Imwani mowa pang'ono.
• Chitani masewera olimbitsa thupi masiku ambiri sabata.
• Sambani khungu lanu mofatsa.
• Sambani nkhope yanu kawiri patsiku ndipo mutatha thukuta kwambiri.
• Lekani kugwiritsa ntchito mankhwala osamalira khungu omwe amaluma kapena kuwotcha.

Kodi Sinclair amalangiza chiyani?

David Sinclair Atenga:

Resveratrol - 1g / tsiku ndi tsiku - m'mawa ndi yogurt (onani komwe mungagule) Nicotinamide Mononucleotide (NMN) - 1g / tsiku lililonse - m'mawa (onani komwe mungagule) Metformin (mankhwala osokoneza bongo) - 1g / tsiku lililonse - 0.5g m'mawa & 0.5g usiku - kupatula masiku omwe mumachita masewera olimbitsa thupi.

Kodi Nmn ili ndi zoyipa?

Mukamamwa pakamwa: Nicotinamide riboside ndi POSSIBLY SAFE ikagwiritsidwa ntchito kwakanthawi. Zotsatira zoyipa za nicotinamide riboside nthawi zambiri zimakhala zofatsa. Zotsatira zoyipazi zimatha kukhala ndi vuto lakumimba monga kunyansidwa ndi kuphwanya kapena mavuto akhungu monga kuyabwa ndi thukuta kwambiri.

Zotsatira zoyipa za resveratrol ndi ziti?

Mukamamwa pakamwa: Resveratrol NDI YOFUNIKA KWAMBIRI mukamagwiritsa ntchito kuchuluka komwe kumapezeka mu zakudya. Mukamamwa mankhwalawa mpaka 1500 mg tsiku lililonse kwa miyezi itatu, resveratrol ndi POSSIBLY SAFE. Mlingo wokwera mpaka 3-2000 mg tsiku lililonse wagwiritsidwa ntchito mosamala kwa miyezi 3000-2. Komabe, kuchuluka kwa resveratrol kotereku kumatha kubweretsa zovuta m'mimba.

Kodi nicotinamide ndiyotetezeka kumwa tsiku lililonse?

Nicotinamide riboside ndiyotetezeka ndi zovuta zochepa - ngati zilipo. M'maphunziro aumunthu, kutenga 1,000-2,000 mg patsiku sikunakhale ndi zotsatirapo zoipa. Komabe, maphunziro ambiri aanthu ndi achidule ndipo amakhala ndi ochepa omwe amatenga nawo mbali. Kuti mumve bwino za chitetezo chake, maphunziro aumunthu olimba amafunikira.

Chifukwa chiyani NADH yochuluka kwambiri?

Kuchulukitsitsa kwa NADH kumeneku kumatha kusokoneza kuchepa kwa redox pakati pa NADH ndi NAD +, ndipo pamapeto pake kumatha kubweretsa kupsinjika kwa oxidative ndi mitundu ingapo yama syndromes amadzimadzi.

Kodi Nmn kapena NR yabwinoko ndi iti?

NR nthawi zambiri imalingaliridwa kuti ndiyotsogola bwino kwambiri ku NAD +, koma m'bale wake wa mamolekyulu a NMN, ngakhale kuti siophatikizira ku Basis, akukweza nsidze ngati mwana watsopano pamalopo.

NMN ndi yayikulu kuposa NR, kutanthauza kuti nthawi zambiri imafunika kuthyoledwa kuti igwirizane ndi selo. NR, poyerekeza ndi ena oyamba a NAD + (monga nicotinic acid kapena nicotinamide) amalamulira bwino kwambiri. Koma ipatseni NMN khomo latsopano, lomwe lingakwaniritse, ndipo ndimasewera atsopano.

Kodi zabwino zowonjezera za Nmn ndi ziti?

• Ndi Nmn supplement yiti yabwino kwambiri?
• Mapale a NMN Sublingual.
• NAD + Liposomal Golide NMN.
• Makapisozi a NMN.

Kodi Nmn amasintha ukalamba?

Njira zolimbikitsira kuwonjezeka kwa milingo ya NAD + zawonetsedwa kuti zikuthandizira kugwira ntchito kwa mitochondrial m'zinyama zakale, ndikusintha zina zomwe zimawonongeka ndi ukalamba. Kuwongolera kwa nicotinamide mononucleotide (NMN) kwawonetsedwa kuti kuthana ndi zovuta zokhudzana ndi ukalamba.

Muyenera kutenga ndalama zingati?

Pomwe kafukufuku watsimikizira kuti Nicotinamide Mononucleotide kapena NMN ndiyabwino kuti anthu agwiritse ntchito, kafukufuku akuchitikabe kuti apeze kuchuluka kwa kuchuluka kwa kuchuluka kwa kuchuluka kwa NMN mwa anthu. Komabe, maphunziro omwe apangidwa pakadali pano atsimikizira kuti kuchuluka kwa 500 mg patsiku ndikotetezeka kwa amuna. Masiku ano, Nicotinamide Mononucleotide imapezeka m'njira zosiyanasiyana, kuphatikizapo mapiritsi ndi ufa. Ogulitsa othandizira a NMN amati zowonjezera pakamwa ndizothandiza kwambiri pakukweza kupanga kwa NAD + m'thupi. Izi zimadalira kuti Slc12a8, nicotinamide nucleotide transporter, imathandizira kuyamwa kwa NMN m'matumbo.

Kodi Nmn ndiyofanana ndi b3?

NMN sichoncho. NMN si mtundu wa vitamini B3, ndipo palibe mayesero azachipatala kutsimikizira kuti ikuwonjezera NAD mwa anthu. NMN siyonso mtundu wa molekyulu womwe ungaganizidwe ngati vitamini chifukwa uli ndi phosphate, yomwe imakhudza kuthekera kwake kulowa m'maselo.

Ndi chakudya chiti chomwe chili ndi NAD + yochuluka kwambiri?

Zakudya Zomwe Zimalimbikitsa Milingo ya NAD

Pali zakudya zina zomwe zitha kulimbikitsa ma NAD mthupi. Ena mwa iwo ndi awa:

• Mkaka Wamkaka - Kafukufuku wasonyeza kuti mkaka wa ng'ombe ndi gwero labwino la Riboside Nicotinamide (RN). Lita imodzi ya mkaka wa ng'ombe watsopano uli ndi pafupifupi 3.9µmol wa NAD +. Chifukwa chake pamene mukusangalala ndi mkaka wotsitsimula, mukukhala kuti mukukhala achichepere komanso athanzi!
• Nsomba - nachi chifukwa china choti musangalale ndi nsomba! Mitundu ina ya nsomba ngati tuna, salimoni ndi sardini ndizambiri za NAD + m'thupi.
• Bowa - anthu ambiri amakonda bowa ndipo amakhala chakudya pachakudya chawo. Koma kodi mumadziwa kuti bowa, makamaka bowa wa crimini, amathandizanso kukulitsa milingo ya NAD mwachilengedwe? Inde, ndizoona. Chifukwa chake, sangalalani kudya bowa ndikupitilizabe kuwoneka ocheperako komanso achichepere!
• Yisiti - yisiti ndi chinthu chomwe chimagwiritsidwa ntchito popanga buledi ndi zinthu zina zophika buledi. Yisiti ili ndi Riboside Nicotinamide (RN), yomwe ndi cholosera cha NAD. Nachi chifukwa china choti musangalale ndi mitanda kapena buns yomwe mumakonda mukamapita kuphika buledi! Sangalalani ndi chakudya chomwe mumakonda kwinaku mukukulitsa milingo ya NAD nthawi yomweyo. Ndizabwino bwanji!
• Masamba Obiriwira - masamba obiriwira ali ndi mitundu yonse ya michere yomwe imapindulitsa m'njira zosiyanasiyana. Posachedwa, zadziwika kuti masamba obiriwira nawonso ndi gwero labwino la NAD mthupi. Ena mwa ndiwo zamasamba ndi monga nandolo ndi katsitsumzukwa.
• Mbewu Zonse - monga tafotokozera kale, Vitamini B3 imakhalanso ndi RN, yomwe imayambitsa NAD. Komabe, masamba, zakudya kapena mbewu zikaphikidwa kapena kukonzedwa, amataya zakudya komanso mavitamini. Chifukwa chake, tikulimbikitsidwa kuti muyeneranso kudya ndiwo zamasamba zosaphika ndikudya nyemba zonse m'malo mwa zakudya zopangidwa.
• Chepetsani Zakumwa Zakumwa Mowa - NAD ndiyomwe imayang'anira njira zonse zomwe thupi limagwiritsira ntchito. Mowa umasokoneza njirazi ndikuchepetsa mphamvu ya NAD. Chifukwa chake, muyenera kupewa kumwa mopitirira muyeso popeza nawonso siabwino pathanzi lanu.

Kodi Nmn imayambitsa kusefukira?

'Niacin flush' ndi zotsatira zoyipa zakumwa kwambiri kwa supplementation niacin (Vitamini B3). Kutuluka kumachitika pamene niacin imapangitsa kuti ma capillaries ang'onoang'ono pakhungu lanu achepetse, zomwe zimapangitsa kuti magazi aziyenda bwino pakhungu. Mosiyana ndi mavitamini B3 (niacin) othandizira, nicotinamide riboside sayenera kuyambitsa nkhope.

Kodi ndingagule kuti Nmn ku Canada?

NMN ndi nucleotide yochokera ku ribose ndi nicotinamide. Monga nicotinamide riboside (Niagen), NMN ndi chochokera ku niacin, komanso cholozera cha NAD +. NMN Canada: Nicotinamide mononucleotide sikupezeka pakadali pano ngati chowonjezera ku Canada.

NMN ndi nucleotide yochokera ku ribose ndi nicotinamide. Monga nicotinamide riboside (Niagen), NMN ndi chochokera ku niacin, komanso cholozera cha NAD +. NMN Canada: Nicotinamide mononucleotide sikupezeka pakadali pano ngati chowonjezera ku Canada.

Kodi Nmn ndi yotetezeka?

Kwa zaka zambiri, kafukufuku wachitika kuti apeze ngati kugwiritsa ntchito NMN mwa anthu kuli kotetezeka kapena ayi. Maphunzirowa awulula, mobwerezabwereza kuti kugwiritsa ntchito Nicotinamide Mononucleotide ndikotetezeka kotheratu pamene mulingo wake uli wochepa. Mwambiri, abambo amalangizidwa kuti azitsatira tsiku lililonse zosakwana 500 mg. Komabe, ziyenera kukumbukiridwa kuti a FDA sanavomereze NMN ngati mankhwala otetezeka. Chifukwa chake, ngati muli ndi ziwengo zilizonse kapena zovuta zamankhwala, ndibwino kuti mufunsane ndi dokotala musanayambe zowonjezera za NMN.

Kodi NAD kapena NMN yabwinoko ndi iti?

NAD ndi NMN ndizodziwika bwino zotsutsana ndi kukalamba zowonjezera, ndipo pazifukwa zomveka.

Kodi ndingatani kuti ndiwonjezere NAD + yanga mwachilengedwe?

Kulimbikitsa Mwachilengedwe NAD

• Kusala kudya
• Zowonjezera Zakudya za Nicotinamide Riboside
• Masewera olimbitsa thupi
• Dzuwa Lochuluka Silingakhale Labwino!
• Zakudya Zomwe Zimalimbikitsa Milingo ya NAD

Ndiyenera kubweretsa chiyani ndi NMN?

Kuti musinthe magawo anu a NAD, mutha kutenga makapisozi a NMN omwe atulutsidwa mochedwa ndi Sirtuin Activator monga Resveratrol wokhala ndi yogurt wamafuta wathunthu omwe amathandizira kupezeka kwa Resveratrol.

Kodi ndiyenera kutenga TMG ndi NMN?

Ngati mukugwiritsa ntchito NMN kapena mukuganiza zoyambira, lingalirani kuyiphatikiza ndi TMG ngati chithandizo chowonjezera cha methylation. Othandizira ena a methyl omwe angakhale othandiza ndi monga methylated B6, B12, ndi folate.

Kodi pali kusiyana kotani pakati pa nicotinamide ndi nicotinamide riboside? (3)

Niacin ndi mtundu wa nikotini wokhala ndi oxidized womwe thupi limatha kusintha kukhala NAD. Nicotinamide ndi amide wa niacin omwe amafanana kwambiri ndi NAD ndipo amakhala ndi zovuta zochepa. Nicotinamide riboside ndi mawonekedwe a nicotinamide omwe ali ndi malingaliro osiyanasiyana.

Kodi Nmn ndi niacin?

Monga nicotinamide riboside, NMN ndi chochokera ku niacin, ndipo anthu ali ndi michere yomwe ingagwiritse ntchito NMN kupanga nicotinamide adenine dinucleotide (NADH). Mu mbewa, NMN imalowa m'maselo kudzera m'matumbo ang'onoang'ono mkati mwa mphindi 10 mutembenukira ku NAD + kudzera pa wotumiza wa Slc12a8 NMN.

Kodi nicotinamide riboside m'munsi mwa BP?

Nicotinamide riboside ndiyomwe imachitika mwanjira inayake ya nicotinamide adenine dinucleotide (NAD +), mkhalapakati wofunikira wazotsatira za zoletsa za caloric, chifukwa chake buku loletsa caloric loletsa mimetic. Posachedwapa tamaliza maphunziro oyendetsa ndege a nicotinamide riboside supplementation mwa achikulire athanzi komanso achikulire ndikuwonetsa kuti milungu isanu ndi umodzi yowonjezerapo yachepetsa kuthamanga kwa magazi (SBP) ndi 6 mmHg mwa anthu omwe ali ndi SBP yoyambira ya 8-120 mmHg (SBP yokwera / Matenda a hypertension) poyerekeza ndi placebo, ndikuchepetsa kuwuma kwa mitsempha, wolosera wamphamvu wa CVD ndi matenda ena okhudzana ndi kufa.

Kodi betaine imapezeka kuti?

Betaine amapezeka m'ma microorganisms, zomera, ndi nyama ndipo ndi gawo lofunikira pazakudya zambiri, kuphatikiza tirigu, nkhono, sipinachi, ndi beets. Betaine ndi zwitterionic quaternary ammonium compound yomwe imadziwikanso kuti trimethylglycine, glycine betaine, lycine, ndi oxyneurine.

Ndi zakudya ziti zomwe zimasiya makwinya?

Nazi zakudya 10 zabwino kwambiri zotsutsa ukalamba kuti zisamalire thupi lanu ndi kuwala komwe kumachokera mkati.

• Watercress
• Tsabola wofiyira belu
• papaya
• blueberries
• Burokoli
• sipinachi
• mtedza
• Mbatata zokoma
• Mbewu za makangaza

Kodi ndingaoneke wachichepere zaka 10?

• Gwiritsani Ntchito Chigoba Chosungunula.
• Sankhani Maziko Owala
• Pewani Tsitsi Lanu Pang'ono
• Valani Ponytail
• Kutulutsa (Koma Osapitilira Izi)
• Yeretsani Mtsinje Wanu Wamadzi
• Malizitsani Kuyang'ana Pang aonoting'ono

Kodi ndingaletse bwanji nkhope yanga kuti isakalambe?

• Tetezani khungu lanu padzuwa tsiku lililonse
• Ikani chofufuta nsalu m'malo mozipeza
• Ngati mumasuta, siyani
• Pewani kubwereza nkhope
• Idyani chakudya chopatsa thanzi, chopatsa thanzi
• Imwani mowa pang'ono
• Gwiritsani ntchito masiku ambiri a sabata
• Sambani khungu lanu mofatsa

Ndi zakudya ziti zomwe zimakupangitsani msinkhu msanga?

1. Zakudya zokoma za mbatata za batala la ku France
2. Wophukira mkate wa mkate woyera
3. Uchi kapena zipatso za shuga woyera
4. Mafuta a azitona kapena mapeyala a margarine
5. Khalani ndi nkhuku za nyama zomwe zasinthidwa
6. Muzimva mkaka
7. Ganizirani kawiri za soda ndi khofi
8. Imwani mowa pang'ono
9. Pewani kuphika ndi kutentha kwambiri
10. Sungani mikate ya mpunga
11. Kulimbana ndi fructose ndi lipoic acid

Kodi ndi vitamini uti wabwino pamakwinya amaso?

Vitamini C amathanso kuthandizira kuthana ndi zizindikilo za ukalamba chifukwa chofunikira kwambiri pakapangidwe kanyama ka collagen. Zimathandiza kuchiritsa khungu lowonongeka ndipo, nthawi zina, amachepetsa makwinya. Kudya mavitamini C okwanira kumathandizanso kukonza ndikupewa khungu louma.

Chifukwa Chiyani Timafunikira Nicotinamide Mononucleotide (NMN)?

Kukalamba ndizokhudzana ndi nthawi komanso kuthandizidwa kwakanthawi pantchito zamunthu. Ngakhale kukalamba kuli kosapeweka komanso kosapeweka, asayansi apereka zaka kuti amvetsetse momwe njirayi ingachedwetsedwe ndikuwongoleredwa. Kafukufuku wopitilira uyu wadzetsa kupezeka kwa zinthu zingapo ndi mankhwala okhala ndi zinthu zotsutsana ndi ukalamba zomwe zimatha kusandulika kukhala zowonjezera zowonjezera. Chimodzi mwazinthu zotere zomwe zili ndi zotsutsana ndi ukalamba zomwe asayansi akumachita chidwi ndi NMN kapena Nicotinamide Mononucleotide. Munkhaniyi, tikambirana zonse zomwe mungadziwe za NMN komanso chowonjezera chotsutsana ndi kukalamba cha nicotinamide mononucleotide mu 2022.

Kugwiritsa ntchito kwa Nicotinamide Mononucleotide (NMN)

Mpaka zaka zingapo zapitazo, maphunziro onse okhudzana ndi kugwiritsa ntchito kwa NMN anali kuchitidwa pazinyama ndipo pomwe maphunziro awa adawonetsa zotsatira zabwino, zotsatirazi sizinali zokwanira kukhazikitsa zabwino zogwiritsa ntchito kwa NMN mwa anthu. Mu 2016, kafukufuku adachitika kuti awunikire chitetezo cha kugwiritsa ntchito kwa NMN komanso nthawi yake m'magazi aanthu. Kafukufukuyu adabweretsa zotsatira zabwino. Pambuyo pake, kafukufuku wina adachitika mu 2016 kuti aphunzire momwe kugwiritsa ntchito kwa NMN kumagwiritsira ntchito azimayi achikulire 50 omwe ali ndi vuto lalikulu la BMI, magazi m'magazi, ndi triglycerides yamagazi. Phunzirolo linayenda bwino. Komabe, popeza malo owerengerawa amangolembedwa kwa azimayi azaka zakubadwa, asayansi amakhulupirira kuti umboni wina umafunika kuti atsimikizire ngati kugwiritsa ntchito NMN ndikotetezeka kwa anthu.

Chifukwa chake, posachedwa, mu 2019, kafukufuku adachitika ku Clinical Trial Unit ya Keio University School of Medicine. Nkhani ya phunziroli inali amuna a 10 azaka zapakati pa 40 ndi 60. Amunawa ankapatsidwa mlingo kuchokera ku 100 mg mpaka 500 mg. Kafukufukuyu adatsimikizira kuti NMN imaloledwa bwino ndi anthu ndipo ndi yotetezeka kuti idye malinga ngati kugwiritsidwa ntchito kwake kumayendetsedwa bwino. Kafukufukuyu anali wofunikira chifukwa anali kafukufuku woyamba wa NMN wochitidwa pa anthu kuti aphunzire momwe NMN imakhudzira thanzi la munthu. Zitangokhazikitsidwa kuti kugwiritsa ntchito NMN kuli kotetezeka, opanga anayamba kugulitsa msika ndi zowonjezera za NMN, zomwe zafala kwambiri masiku ano.

ubwino

M'chigawo chino, tikambirana za maubwino omwe angabwere chifukwa cha Nicotinamide Mononucleotide kapena NMN

① NMN Imachedwetsa Ukalamba

Chimodzi mwamaubwino akulu a NMN ndikuti amachepetsa ukalamba. Zaka zingapo zapitazo David Sinclair, wodziwika bwino wa Australia Biologist komanso pulofesa wa Genetics, adapereka umboni kuti NAD + imachedwetsa ukalamba komanso kuyambika kwa matenda okhudzana ndi zaka. Komabe, kupanga kwa NAD + kumacheperanso ndi zaka. Chifukwa chake, pamene anthu akukalamba, kufunikira kwa wotsogolera wa NAD + kumawonjezeka m'matupi awo. Apa ndipomwe NMN imayamba kugwira ntchito: NMN imalowa m'maselo ndikusintha ma khemedwe angapo asanafike mu NAD + ndikuchepetsa njira zoyendetsera zaka.

② Anthu Omwe Ali Ndi Matenda A Shuga Angapindule Ndi Kudya Kwawo

Kafukufuku adachitika kuti aphunzire momwe zowonjezera pakamwa za NMN zimathandizira pakudya ndi matenda okhudzana ndi shuga a zaka za mbewa. Kafukufukuyu adawonetsa kuti mbewa zomwe zimaperekedwa pakamwa NMN zowonjezera zimawonetsa chidwi cha insulini komanso kubisala kwake. Kafukufukuyu adapereka chidziwitso chakuti Nicotinamide Mononucleotide kapena zowonjezera pakamwa za NMN zitha kuthandiza anthu omwe ali ndi matenda a shuga.

③ Kugwiritsa Ntchito NMN Kumalumikizidwanso Ndi Kupititsa Patsogolo Moyo Waumoyo

Kafukufuku wina adapangidwa kuti aphunzire momwe zowonjezera za NMN zimakhudzira thanzi la mbewa Kafukufukuyu adawonetsa kuti NMN sinangobweza zotengera zamagazi zokhudzana ndi msana komanso kuwonongeka kwa capillary mu mbewa komanso zimapangitsa kuti magazi aziyenda bwino. Chomwe chinali chodabwitsa kwambiri ndichakuti mbewa zomwe zimapatsidwa NMN zowonjezera pakamwa, kuphulika kwa mitsempha yatsopano ya magazi kunawonedwa. Posachedwa, kafukufuku wina anachitidwa kuti adziwe momwe NMN imakhudzira thanzi la mbewa ndipo kafukufukuyu nawonso adawonetsa zotsatira zofananazo. Maphunzirowa apereka umboni wokwanira kwa ofufuza kuti akhulupirire kuti kumwa NMN kumathandizanso thanzi la mtima mwa anthu.

Nicotinamide Mononucleotide (NMN)

④ Anthu omwe ali ndi Alzheimer's Atha Kupindula ndi Kugwiritsa Ntchito NMN

Mwa anthu omwe akudwala matenda a Alzheimer's, milingo ya NAD imatsika kwambiri. Chifukwa chake, anthu omwe ali ndi matenda a Alzheimer's akudya NMN, thupi limagwira ndikuwonjezera kuchuluka kwa NAD +, komwe kumabweretsa kuwongolera magalimoto, kuwonjezera zochita za majini a SIRT3, kukumbukira bwino, ndikuchepetsa neuroinfigueation. Chifukwa chake, anthu omwe ali ndi matenda a Alzheimer's atha kupindula ndi kudya NMN.

⑤ NMN Iyambitsanso Ntchito Ya Impso

Supplementation ya Oral NMN imalumikizidwa ndi kusintha kwa impso. Izi ndichifukwa chakuti NMN imawonjezera kupanga kwa NAD + ndi SIRT1, zonse ziwiri zomwe zimalumikizidwa ndi ntchito yothandiza impso.

Kodi Mungagule Kuti Ufa wa Nicotinamide Mononucleotide (NMN) mu Bulk?

Ngati mukufuna kugula ufa wa Nicotinamide Mononucleotide (NMN) wochuluka, malo abwino kwambiri ogulira ufa wa NMN ndi cofttek.com. Cofttek ndi kampani yopanga zida zapamwamba kwambiri zomwe zakhala zikupanga zinthu zatsopano komanso zapamwamba kuyambira 2008. Kampaniyo ili ndi gulu lochititsa chidwi la R&D lokhala ndi anthu odziwa zambiri omwe apanga chitukuko cha zopikisana. Cofttek ali ndi zibwenzi ndipo amapereka zogulitsa zake ku makampani azachipatala ku China, Europe, India, ndi North America. Β-Nicotinamide Mononucleotide yoperekedwa ndi Cofttek ndiyabwino kwambiri komanso yotetezeka kwathunthu kuti anthu adye. Chofunika kwambiri, kampaniyi imapereka ufawu mochuluka, mwachitsanzo mu mayunitsi a 25kgs. Chifukwa chake, ngati mukuyang'ana ku gulani ufa uwu mochuluka, Cofttek ndi kampani yomwe muyenera kulumikizana nayo - ndiomwe amapereka bwino kwambiri pamsika wa Nicotinamide Mononucleotide (NMN).

Zothandizira

(1). Yao, Z., ndi al. (2017). Nicotinamide Mononucleotide Imaletsa Kuyambitsa kwa JNK Kuthetsa Matenda a Alzheimer.

(2). Yoshino, J., ndi al. (2011). Nicotinamide Mononucleotide, NAD (+) Wapakatikati, Amathandizira Pathophysiology ya Zakudya ndi Matenda a Shuga Omwe Amakhudzidwa Ndi Zaka mu mbewa. Cell kagayidwe.

(3). Yamamoto, T., ndi al. (2014). Nicotinamide Mononucleotide, Wapakati pa NAD + Synthesis, Imateteza Mtima ku Ischemia ndi Reperfusion.

(4). Wang, Y., et al. (2018). NAD + Supplementation Normal Alzheimer's Features and DNA Damage Responses in a New AD Mouse Model yokhala ndi Kutulutsa Koyeserera kwa DNA.

(5). Keisuke, O., ndi al. (2019). Zotsatira za Kusintha kwa NAD Metabolism mu Mavuto Amagetsi. Zolemba pa Sayansi Yachilengedwe.

(6). Ulendo wofufuza egt.

(7). Oleoylethanolamide (oea) -wotenga zamatsenga m'moyo wanu.

(8). Anandamide vs cbd: ndi iti yomwe ili yabwinoko ku thanzi lanu? Chilichonse chomwe muyenera kudziwa za iwo!

(9). Chilichonse chomwe muyenera kudziwa za nicotinamide riboside chloride.

(10). Mankhwala a magnesium l-threonate: maubwino, kuchuluka kwake, ndi zotsatirapo zake.

(11). Palmitoylethanolamide (mtola): ubwino, mlingo, ntchito, zowonjezera.

(12). Mapindu apamwamba 6 azaumoyo a resveratrol othandizira

(13). Mapindu 5 apamwamba akumwa phosphatidylserine (ps)

(14). Maubwino apamwamba 5 otenga pyrroloquinoline quinone (pqq).

(15). Chithandizo chabwino kwambiri cha alpha gpc.