Ngati mukufuna Nicotinamide wamasamba Riboside mankhwala enaake supplement, timalangiza Cofttek Nicotinamide Riboside supplement. Kampani yopanga imangogwira ndi zowonjezera za Nicotinamide Riboside motero, munthu akhoza kukhala wotsimikiza kuti zowonjezera zomwe kampaniyo amapanga ndizapamwamba kwambiri. Pulogalamu ya Cofttek Nicotinamide Riboside supplement imabwera mu makapisozi osavuta kudya, omwe ndi osavuta kumeza. Ogwiritsa akuyenera kutenga kapisozi kamodzi patsiku.
Komabe, ngati mukuyang'ana gilateni, dzira, BPA, mtedza, zotetezera komanso zopanda mkaka, tikukulimbikitsani kuyika ndalama zanu mu Cofttek Nicotinamide Riboside supplement. Chowonjezera ichi chimaphatikiza NR ndi flavonoids. Pamodzi, izi ziwiri zimathandizira ntchito ya sirtuin. Chofunika kwambiri, Cofttek akuti imayeza mayeso anayi pachowonjezera chake motero, zowonjezera kampaniyo ndizotetezeka bwino. Kuphatikiza apo, zowonjezera izi zimapangidwa m'malo ovomerezeka a cGMP komanso malo ovomerezeka a TGA

Kodi Nikotinamide Riboside Chloride ndi chiyani?

Nicotinamide Riboside Chloride kapena Niagen ndi mtundu wamakristali wa Nicotinamide Riboside, womwe ndi vitamini wa NAD + precursor. Ngakhale Nicotinamide Riboside akulemera 255.25 g / mol, Nicotinamide Riboside Chloride amalemera 290.70 g / mol ndi 100 mg ya Nicotinamide Riboside Chloride amapereka 88 mg ya Nicotinamide Riboside. NR imawoneka yotetezeka kugwiritsidwa ntchito muzakudya.

Ngakhale Nicotinamide Riboside ndi mtundu wa Vitamini B3, mawonekedwe ake osiyanasiyana amawapangitsa kukhala osiyana kwambiri ndi ena ambiri a gulu la Vitamini B3, monga nicotinamide ndi niacin. Ngakhale Niacin amachititsa kuti khungu lizituluka poyambitsa GPR109A G-protein coupept receptor, Nicotinamide Riboside sachitapo kanthu ndi cholandilira ichi motero, samachititsanso kuti khungu liziziririka, ngakhale mutamwa mankhwala okwanira 2000 mg patsiku. Kupitilira apo, kuyesa komwe kunachitika pa mbewa kudavumbulutsa kuti Nicotinamide Riboside ndiye NAD + wotsogola yemwe adatsogolera kuyimba kwambiri ku Nicotinamide Adenine Dinucleotide kapena NAD + mkati mwa thupi.

Nicotinamide Riboside imachitika mwachilengedwe mu chakudya chamunthu ndipo kamodzi mkati mwa thupi, imasinthika kukhala NAD +, yomwe thupi limafunikira ntchito zosiyanasiyana. Mwachitsanzo, kafukufuku wasayansi watsimikizira kuti Nicotinamide Riboside Chloride kapena NAD + yoperekedwa ndi NR imawongolera ntchito ya mitochondrial komanso kumva kwa insulin poyambitsa banja la sirtuin la ma enzymes, omwe amachititsa kayendedwe ka oxidative metabolism.

Pakadali pano, maphunziro asanu apangidwa kuti aphunzire za chitetezo ndi mphamvu ya Nicotinamide Riboside ndipo maphunziro onsewa apeza kuti poti chitetezo chimagwiritsidwa ntchito ndi anthu.


Chifukwa Chomwe Tifunikira Nicotinamide Riboside Chloride

Makampani opanga zodzikongoletsera ndiopanga madola biliyoni, makamaka chifukwa choti anthu amatengeka kwambiri ndi mawonekedwe awo. Ichi ndichinthu chofunikira kwambiri kuti kafukufuku wazinthu zopewera kukalamba ndi zinthu zake apita patsogolo modabwitsa munthawi yochepa. Mabungwe apadziko lonse lapansi amvetsetsa kuti pali ndalama zopangidwa kuchokera ku chikhumbo cha anthu kuti akhalebe achichepere kwanthawizonse, motero, akhale ndi magulu m'malo, akupereka masiku ndi milungu kuti apeze zosakaniza ndi zinthu zomwe zingalimbikitse thanzi la khungu. Nicotinamide Riboside kapena Niagen idapezeka chifukwa chofunafuna kosalekeza kwa zinthu zotsutsana ndi ukalamba. Ngakhale zinthu zambiri zotsutsana ndi ukalamba zimachepetsa zizindikilo zakukalamba pakhungu, Niagen amachepetsa zizindikilo zakukalamba mthupi. Nicotinamide Riboside kapena Niagen ndi mawonekedwe a kristalo a Nicotinamide Riboside mankhwala enaake ndipo kamodzi mkati mwa thupi, imasinthika kukhala NAD +, yomwe imayang'anira kukalamba wathanzi komanso ntchito zina zofunika kwambiri.

Munkhaniyi, tikamba za mbali zonse za pangani zodabwitsazi, kuphatikiza maubwino, zotsatira zoyipa ndi zotsatira zoyenera.

Nicotinamide-Riboside-mankhwala enaake
Nicotinamide-Riboside-mankhwala enaake

Kodi Nikotinamide Riboside Chloride Otetezeka?

Kafukufuku angapo omwe adachitika pakadali pano apeza kuti kumwa kwa Nicotinamide Riboside mu 1000 mpaka 2000 mg patsiku ndikotetezeka kuti anthu azigwiritsa ntchito. Komabe, popeza maphunziro a konkriti ambiri amafunika m'derali, opanga Nicotinamide Riboside amalimbikitsa kuti munthu azidya NR tsiku ndi tsiku pansi pa 250-300 mg patsiku.

Ngakhale Nicotinamide Riboside kapena Nicotinamide Riboside Chloride kumwa ndikotetezeka, kumatha kuyambitsa zovuta zina monga nseru, kupweteka mutu, kudzimbidwa, kutopa ndi kutsegula m'mimba. Ngati mukukumana ndi zina mwazizindikirozi mukamamwa mankhwala enaake a NR, nthawi yomweyo funsani dokotala wanu. Komanso, popeza palibe umboni wokwanira wokhudzana ndi momwe Nicotinamide Riboside imathandizira pa amayi apakati ndi oyamwitsa, gululi liyenera kusiya kugwiritsa ntchito mankhwala a Nicotinamide Riboside.

Nicotinamide Riboside ChlorideBwino

Tisanakambirane za maubwino a Nicotinamide Riboside Chloride, ndikofunikira kufotokozera kuti popeza Nicotinamide Riboside Chloride ndiye mchere womwe Nicotinamide Riboside amachokera, zabwino za Nicotinamide Riboside Chloride ndizofanana ndi zabwino za Nicotinamide Riboside.

Nicotinamide-Riboside-mankhwala enaake

① Nicotinamide Riboside Chloride Imalimbikitsa Ukalamba Wathanzi

NAD + yotsegulidwa ndi Nicotinamide Riboside Chloride mkati mwa thupi imayambitsa ma enzyme omwe amalumikizidwa ndi ukalamba wathanzi. Enzyme yotereyi ndi ma sirtuin, omwe amalumikizidwa ndi moyo wabwino komanso wamoyo wazinyama. Kafukufuku wasayansi atsimikizira kuti ma sirtuins amatukula moyo komanso kukhala ndi moyo wautali pochepetsa kutupa, kukulitsa maubwino omwe amabwera chifukwa choletsa kalori ndikukonzanso DNA yowonongeka. NAD + yotsegulidwa ndi Nicotinamide Riboside Chloride imayambitsanso Poly polymerases omwe amadziwika kukonza DNA yowonongeka. Kuphatikiza apo, maphunziro angapo asayansi adalumikiza zochitika za ma polymerases ndi nthawi yowonjezera ya moyo. (1)Conze, D., Brenner, C. & Kruger, CL Chitetezo ndi Metabolism Yanthawi yayitali

② Amachepetsa Mpata Woti Munthu Akhale Ndi Matenda A mtima

Kukalamba kumathandizanso kuti munthu akhale ndi matenda amtima. Anthu akamakalamba, mitsempha yawo yamagazi imayamba kukhala yolimba komanso yolimba, kenako, imayambitsa kuthamanga kwa magazi. Kuthamanga kwa magazi mkati mwa zotengera kumachuluka, mtima umayenera kugwira ntchito molimbika mopopera magazi, zomwe zimabweretsa matenda amtima osiyanasiyana. NAD + yoperekedwa ndi Nicotinamide Riboside Chloride imasintha zosintha zokhudzana ndi ukalamba zomwe zimayambitsa mitsempha yamagazi. Pali umboni wokwanira wasayansi wotsimikizira kuti Nicotinamide Adenine Dinucleotide kapena NAD + sikuti imangochepetsa kuuma kwa mitsempha yamagazi komanso imayendetsa kuthamanga kwa magazi kwa systolic.

③ Nicotinamide Riboside Chloride Imaperekanso Chitetezo ku Maselo Aubongo

Nicotinamide Riboside amateteza maselo amubongo. Kafukufuku wopangidwa pa mbewa adawonetsa kuti kupanga NR-komwe kunayambitsa NAD + kudakulitsa kupanga kwa protein ya alpha ya PGC-1 mpaka 50%. Puloteni ya PGC-1 ya alpha imathandizira kuteteza ma cell am'magazi motsutsana ndi kupsinjika kwa oxidative komanso kumathandizira magwiridwe antchito a mitochondrial. Chifukwa chake, kumwa kwa NR mwa anthu kumateteza ku matenda obwera chifukwa cha ukalamba, monga Alzheimer's ndi Parkinson. Kafukufuku wina adafufuza momwe magulu a NAD + amakhudzira anthu omwe akudwala Parkinson. Kafukufukuyu adatsimikiza kuti NAD + idasintha magwiridwe antchito a mitochondrial m'maselo am'magazi.

Nicotinamide-Riboside-mankhwala enaake

Benef Ubwino Wina Wina wa Nicotinamide Riboside Chloride

Kuphatikiza pazopindulitsa zomwe tafotokozazi, apa ndi zina zowonjezera zochepa zomwe zimagwirizanitsidwa ndi Nicotinamide Riboside Chloride.

i.NR imadziwika kuwonjezera mphamvu ya minofu, kugwira ntchito komanso kupirira chifukwa chake, kugwiritsidwa ntchito kwa NR kumalumikizidwa ndi magwiridwe antchito abwinoko.

ii.Monga tafotokozera pamwambapa, kupanga NR-komwe kumapangitsa NAD + kukonzanso DNA yowonongeka ndikuteteza ku kupsinjika kwa oxidative. Izi, zimachepetsanso mwayi wokhala ndi khansa.

iii.Kafukufuku adafufuza momwe Nikotinamide Riboside amakhudzira kagayidwe ka mbewa. Phunziroli lidatsimikiza kuti NR idakulitsa kagayidwe ka mbewa. Ngakhale umboni wofunikira wasayansi ukufunika pankhaniyi, asayansi ambiri amakhulupirira kuti Nikotinamide Riboside ingakhudzenso anthu motero, iyenera kukhala yothandiza pakuchepetsa thupi.

Mlingo wa Nicotinamide Riboside Chloride

Maphunziro asanu omwe adachitika pano adazindikira kuti Nicotinamide Riboside ndiyotetezeka kuti anthu agwiritse ntchito. Komabe, maphunziro awa akhazikitsa otetezeka Nicotinamide Riboside mankhwala enaake malire a anthu pakati pa 1,000 mpaka 2,000 mg patsiku. Komabe, ziyenera kukumbukiridwa kuti maphunziro onse omwe amasanthula chitetezo cha Nicotinamide Riboside anali ndi zitsanzo zazing'ono kwambiri motero, kafukufuku wambiri akufunika m'derali.

Cholinga choyambirira cha Nicotinamide Riboside Chloride kwenikweni ndikupereka thupi la Nicotinamide Riboside Chloride kapena Niagen. Niagen kapena NR nthawi zambiri amapezeka m'mitundu iwiri: mapiritsi ndi makapisozi. Opanga ambiri a Nicotinamide Riboside othandizira amaphatikiza NR ndi mankhwala ena, monga Pterostilbene. Mulimonsemo, kuti mukhale otetezeka, opanga ambiri othandizira amalimbikitsa kuti azisunga kudya kwa tsiku ndi tsiku kwa NR pakati pa 250 mpaka 300 mg patsiku.

Kumene Mungagule ufa wa Nicotinamide Riboside Chloride mu Bulk?

Kufunikira kwa mankhwala othandizira ku Nicotinamide Riboside kwachulukanso kwambiri pazaka zingapo zapitazi, makamaka chifukwa Nicotinamide Riboside ali ndi zabwino zambiri. Ngati mukufuna kusinthana ndi msika wothandizira wa Nicotinamide Riboside, chinthu choyamba muyenera kuchita ndikupeza kuti ndi wodalirika komanso wodalirika popanga zinthu zopangira. Koti Gulani Nicotinamide Riboside Chloride powder wochuluka? Yankho ndi Cofttek.

Cofttek ndiwophatikiza zida zopangira zinthu zomwe zinayamba kukhalapo mu 2008 ndipo m'zaka khumi zokha, kampaniyo yakhazikitsa kukhalapo kwawo m'maiko angapo. Kupatula kupanga zinthu zodalirika, kampaniyo imalimbikitsidwanso pakupita patsogolo pantchito za biotechnology, tekinoloje ya mankhwala ndi kuyesa kwa mankhwala. Kampaniyi idadzipatsanso kafukufuku wowoneka bwino, yemwe amathandizira kuti asagulitse ena ogulitsa. The Nicotinamide Riboside Chloride ufa  zoperekedwa ndi kampaniyo zimabwera m'magulu a ma 25 kgs ndipo amatha kudalirika kuti akhale abwino. Kuphatikiza apo, kampaniyo ili ndi gulu labwino kwambiri logulitsa komanso kasitomala lomwe lidzasamalira zosowa zanu zonse komanso mafunso anu munthawi yeniyeni. Izi, ngati mukufuna kugula ufa wa Nicotinamide Riboside Chloride wochuluka, khulupirirani Cofttek yekha ..

Nkhani ndi: Dr. Zeng

Nkhani ndi:

Dr. Zeng

Co-founder, utsogoleri waukulu wa kampani; PhD inalandira kuchokera ku Yunivesite ya Fudan mu organic chemistry. Zoposa zaka zisanu ndi zinayi zokumana nazo zamagulu azipangidwe zamagetsi ndi kapangidwe ka mankhwala; pafupifupi mapepala ofufuza 10 omwe adasindikizidwa m'magazini odalirika, okhala ndi ma patenti opitilira asanu aku China.

Zothandizira

(1).Conze, D., Brenner, C. & Kruger, CL Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) mu Randomized, Double-Blind, Placebo yoyendetsedwa ndi Clinical Trial of Healthy Onenepa Akuluakulu. Sci Rep9, 9772 (2019)

(2).Carlijn ME Remie, Kay HM Roumans, Michiel PB Moonen, Niels J Connell, Bas Haskes, Julian Mevenkamp, ​​Lucas Lindeboom, Vera HW de Wit, Tineke van de Weijer, Suzanne ABM Aarts, Esther Lutgens, Bauke V Schomaker, Hyung L Elfrink, Rubén Zapata-Pérez, Riekelt H Houtkooper, Johan Auwerx, Joris Hoeks, Vera B Schrauwen-Hinderling, Esther Phielix, Patrick Schrauwen, Nicotinamide riboside supplementation alters body body and mifupa minofu acetylcarnitine mozungulira anthu athanzi labwino, The American Journal of Clinical Nutrition, Vesi 112, Kutulutsa 2, Ogasiti 2020, masamba 413-426

[3]. M., Lucas, S., Akerman, I., Seabright, A., Lai, YC, Tennant, DA, Nightingale, P., Wallis, GA, Manolopoulos, KN, Brenner, C.,… Lavery, GG (2019) ). Nicotinamide Riboside Imawonjezera Ukalamba Wamunthu Wamisala NAD + Metabolome ndipo Imapangitsa Zisindikizo za Transcriptomic ndi Anti-inflammatory. Malipoti a selo28(7), 1717-1728.e6.

(4).Nicotinamide riboside chloride ufa

(5).Ulendo wofufuza egt.

(6).Oleoylethanolamide (oea) -wotenga zamatsenga m'moyo wanu.

(7).Anandamide vs cbd: ndi iti yomwe ili yabwinoko ku thanzi lanu? Chilichonse chomwe muyenera kudziwa za iwo!

(8).Chilichonse chomwe muyenera kudziwa za nicotinamide riboside chloride.

(9).Palmitoylethanolamide (mtola): ubwino, mlingo, ntchito, zowonjezera.

(10).Mapindu apamwamba 6 azaumoyo a resveratrol othandizira

(11).Mapindu 5 apamwamba akumwa phosphatidylserine (ps)

(12).Maubwino apamwamba 5 otenga pyrroloquinoline quinone (pqq).

(13).Chithandizo chabwino kwambiri cha alpha gpc.

(14).Chithandizo chabwino kwambiri chotsutsana ndi kukalamba cha nicotinamide mononucleotide (nmn).