Wopanga Oleoylethanolamide (OEA) (111-58-0) - Cofttek

Oleoylethanolamide (OEA) (111-58-0)

April 7, 2020

Oleoylethanolamine (OEA) ndimachitika mwachilengedwe ethanolamide lipid ndi nyukiliya receptor peroxisome proliferator-activated receptor-α (PPAR-α) agonist. Amapangidwa m'matumbo ang'onoang'ono ndipo amalepheretsa kudya kudzera pa PPAR-α.


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum

Oleoylethanolamide (OEA) (111-58-0) kanema

Oleoylethanolamide (OEA) Szizindikiro

Name: Oleoylethanolamide (OEA)
CAS: 111-58-0
Chiyeretso 98%
Makhalidwe a Maselo: C20H39NO2
Kulemera kwa maselo: 325.53 g / mol
Melt Point: 59-60 ° C
Dzina la mankhwala: N-Oleoylethanolamide
Mafanowo: N-Oleoylethanolamine, N- (Hydroxyethyl) oleamide, N- (cis-9-Octadecenoyl) ethanolamine, OEA
InChI Key: SUHOQUVVLLYYQR-MRVPVSSYSA-N
Theka lamoyo: N / A
Kutupa: Soluble ku DMSO, Methanol, Madzi
Zosunga: 0 - 4 C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 C kwa nthawi yaitali (miyezi)
ntchito: Oleoylethanolamide (OEA) ndi metabolite lachilengedwe lomwe limapangidwa pang'ono m'matumbo anu ang'ono. OEA imathandizira kuyang'anira njala, kulemera, mafuta amthupi ndi cholesterol pomangirira ku receptor yomwe imadziwika kuti PPAR-Alpha (Peroxisome proliferator-activated receptor alpha).
Maonekedwe: White powder

Kodi Oleoylethanolamide (OEA) CAS 111-58-0 ndi chiani?

Oleoylethanolamine (OEA) ndimachitika mwachilengedwe ethanolamide lipid ndi nyukiliya receptor peroxisome proliferator-activated receptor-α (PPAR-α) agonist. Amapangidwa m'matumbo ang'onoang'ono ndipo amalepheretsa kudya kudzera pa PPAR-α. OEA imathandiziranso GPR119, lipid yokhala ndi bioactive yokhala ndi zotsatira za hypophagic komanso kunenepa kwambiri.

Oleoylethanolamide (OEA) CAS 111-58-0 maubwino

Oleoylethanolamide (OEA) ndi metabolite lachilengedwe lomwe limapangidwa pang'ono m'matumbo anu ang'ono. OEA imathandizira kuyang'anira njala, kulemera, mafuta amthupi ndi cholesterol pomangirira ku receptor yomwe imadziwika kuti PPAR-Alpha (Peroxisome proliferator-activated receptor alpha). Mwakutero, OEA imachulukitsa kagayidwe ka mafuta m'thupi ndipo imauza ubongo wanu kuti mwakhuta ndipo ndi nthawi yoti musiye kudya. OEA imadziwikanso kuti ichulukitse ndalama zomwe sizichita zolimbitsa thupi.

Oleoylethanolamide (OEA) CAS 111-58-0 Njira Zamachitidwe?

Oleoylethanolamide (OEA) imapangidwa ndikusunthidwa m'matumbo ang'onoang'ono kuchokera ku zakudya zochokera ku oleic acid, monga maolivi. Zakudya zamafuta kwambiri zimalepheretsa kupanga kwa OEA m'matumbo. OEA imachepetsa kudya mwa kuyambitsa homeostatic oxytocin ndi histamine circry komanso hedonic dopamine njira. Pali umboni kuti OEA imathanso kuzindikira ma hedonic cannabinoid receptor 1 (CB1R), kuyambitsa kwake komwe kumalumikizidwa ndi kuchuluka kwa chakudya. OEA imachepetsa mayendedwe a lipid mu adipocytes kuti achepetse mafuta. Kuwalanso zotsatira za OEA pazakudya zopatsa mphamvu ndi metabolidi ya lipid kudzakuthandizira pakutsimikiza kwamapangidwe achilengedwe omwe angapangidwe kuti apange njira zothandizira kunenepa kwambiri.

Oleoylethanolamide (OEA) ndi agonist wa peroxisome proliferator-activated receptor-α (PPAR- α). N- Oleoylethanolamide imapanga chisonyezo cham'mimba chomwe chimalimbikitsa ntchito yayikulu ya dopamine kukhazikitsa mgwirizano pakati pa olamulira a caloric- homeostatic ndi hedonic- homeostatic. Oleoylethanolamide yakhala ikuwunikiridwa ngati kupangika kwa maselo omwe amaphatikizidwa ndi kupambana kwa gastric bypass. N- Oleoylethanolamide ndi agonist wosankhidwa wa GPR55.

Oleoylethanolamide (OEA) CAS 111-58-0 ntchito

Oleoylethanolamide (OEA) amagwira ntchito kuti ayambitse china chake chotchedwa PPAR ndipo nthawi yomweyo amakwera kuwotcha mafuta ndikuchepetsa kusungidwa kwamafuta. Mukamadya, milingo ya OEA imachulukirachulukirabe ndipo chidwi chanu chimachepa pomwe mitsempha yolumikizana ndi ubongo wanu imakuwuzani kuti mwadzaza. PPAR-α ndi gulu la zida zolumikizira ma nyukiliya zomwe zimakhudzana ndi mtundu wa lipid metabolism ndi njira za energyhomeostasis.

Oleoylethanolamide (OEA) ufa Zogulitsa(Koti Mugule Oleoylethanolamide (OEA) ufa wochuluka)

Kampani yathu imakhala ndiubwenzi wamtundu wautali ndi makasitomala athu chifukwa timayang'ana kwambiri ntchito yamakasitomala komanso kupereka zopambana. Ngati muli ndi chidwi ndi malonda athu, timasinthasintha makonda anu kuti agwirizane ndi zosowa zanu ndipo nthawi yathu yotsogoza mwachangu imatsimikizira kuti mudzalawa malonda athu nthawi. Timayang'ananso ntchito zowonjezera phindu. Tili ndi mafunso azithandizo ndi chidziwitso chothandizira bizinesi yanu.

Ndife othandizira Oleoylethanolamide (OEA) ufa kwa zaka zingapo, timapereka zogulitsa ndi mtengo wampikisano, ndipo malonda athu ndi apamwamba kwambiri ndipo amayesedwa mosamala, kudziyesa pawokha kuti awonetsetse kuti ndi otetezeka padziko lonse lapansi.

Zothandizira

  1. Gaetani S, Oveisi F, Piomelli D (2003). "Kusintha kwa mawonekedwe a ufa muzole wa anorexic lipid mediator oleoylethanolamine". Neuropsychopharmacology. 28 (7): 1311-6. doi: 10.1038 / sj.npp.1300166. PMID 12700681.
  2. Lo Verme J, Gaetani S, Fu J, Oveisi F, Burton K, Piomelli D (2005). "Kawongoleredwe kazakudya za oleoylethanolamine". Selo. Mol. Life Sci. 62 (6): 708-16. doi: 10.1007 / s00018-004-4494-0. PMID 15770421.
  3. Gaetani S, Kaye WH, Cuomo V, Piomelli D (Seputembara 2008). "Ntchito za endocannabinoids ndi kufananizira kwake kunenepa kwambiri ndi zovuta za kudya". Idyani Chakudya Cholemetsa. 13 (3): e42-8. PMID 19011363.