Coluracetam (135463-81-9)

Mwina 8, 2021

Cofttek ndiye wopanga ufa wabwino kwambiri wa Coluracetam ku China. Fakitale yathu ili ndi dongosolo lathunthu loyang'anira kupanga (ISO9001 & ISO14001), lomwe limatha kupanga 160kg pamwezi.

 


Chikhalidwe: Mu Kupanga Misa
Unit: 1kg / thumba, 25kg / Drum

Coluracetam (135463-81-9) Szizindikiro

Name: Coluracetam
CAS: 135463-81-9
Chiyeretso 98%
Maselo chilinganizo: C19H23N3O3
Kulemera kwa Maselo: Magalamu 341.411 / moll
Melt Point: N / A
Dzina la mankhwala: N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide

MKC-231

bci-540

Mafanowo: Coluracetam; Zamgululi Zamgululi BCI 540; MKC 231; Zamgululi Mkonzi.
InChI Key: PSPGQHXMUKWNDI-UHFFFAOYSA-N
Theka lamoyo: N / A
Kutupa: Kusungunuka mu DMSO
Zosunga: Wouma, wamdima komanso wa 0 - 4 C kwakanthawi kochepa (masiku mpaka masabata) kapena -20 C kwakanthawi (miyezi mpaka zaka)
ntchito: Mafuta a Raw Coluracetam (MKC-231) ndi mankhwala opangidwa ndi racetam omwe amachitidwa kuti ndi mankhwala a nootropic.
Maonekedwe: white crystalline powder

 

Coluracetam (135463-81-9) NMR Spectrum

Coluracetam (135463-81-9) NMR Spectrum

Ngati mukufuna COA, MSDS, HNMR pagulu lililonse lazogulitsa ndi zina, chonde lemberani oyang'anira malonda.

 

Kodi Coluracetam (135463-81-9)?

Mafuta a Raw Coluracetam (MKC-231) ndi mankhwala opangidwa ndi racetam omwe amachitidwa kuti ndi mankhwala a nootropic. Alibe umboni wochuluka wofufuza izi, koma njira zothandizira (kuphatikizapo kukhazikitsa) zikuwoneka zosiyana kwambiri ndi mankhwala ena a racetam monga Piracetam kapena Aniracetam.

Mafuta a Raw Coluracetam akuwoneka kuti akugwirizana ndi njira yomwe imadziwika kuti yolimba kwambiri ya choline (HACU yaifupi), yomwe ndi gawo la kuchepetsa zojambula zojambula m'kati mwa neuron kuti lizikhala mu neurotransmitter acetylcholine. Kuwonjezeka kwa chiwerengero cha HACU kumawoneka kuti kumawonjezera ntchito ya nelinons ya cholinergic, kotero ndicholinga chofuna kukonzekera kwa chidziwitso.

 

Coluracetam (135463-81-9) ubwino

  • Sinthani Memori ndi Kuphunzira
  • Sinthani Kuwerenga Kumvetsetsa komanso Kukumbukira Kwaulere
  • Kupititsa Kukhazikika Kwa Kachidziwikire
  • Pewani Kuthana ndi Matenda Ochiritsa
  • Kupititsa patsogolo kwa Neurogeneis
  • Itha kukonza kukhumudwa kwa Mental
  • Pangani Zowoneka bwino
  • Kusintha kwa chizindikiro cha Bowel Syndrome
  • Coluracetam zosangalatsa ntchito

 

Coluracetam (135463-81-9) ntchito

Coluracetam (INN) (dzina lachinsinsi BCI-540; kale MKC-231) ufa ndi wothandizira nootropic wa banja la racetam. Poyamba idapangidwa ndikuyesedwa ndi Mitsubishi Tanabe Pharma Corporation ya matenda a Alzheimer's. Mankhwalawa atalephera kufikira kumapeto kwa mayesero ake azachipatala anali ndi chilolezo ndi BrainCells Inc kuti afufuze za vuto lalikulu lachisokonezo (MDD), lomwe linatsogoleredwa ndikupatsidwa "Qualifying Therapeutic Discovery Program Grant" ndi boma la California.

 

Coluracetam (135463-81-9) Mlingo

Kafukufuku ambiri pa coluracetamu anachitidwa pa zinyama m'malo mwa anthu, kotero palibe malamulo ovomerezeka ovomerezeka padziko lonse. Mtundu wa mlingo woyenera umatchulidwa kuti 5-20 mg. Ogwiritsa ntchito coluracetamu awonetsa mitundu yosiyanasiyana ya mankhwala omwe amathandizidwa pamlomo ndi pamagulu.

Ndemanga za ogwiritsa ntchito zanenanso kuti kulolerana ndi ufa wa coluracetam kumatha kukula mwachangu. Monga momwe zimakhalira ndi mankhwala onse, makamaka nootropics, ndibwino kuti muyambe pang'ono pang'ono ndikukweza minyewa pang'onopang'ono thupi lanu likamachita ndikusintha mankhwalawo. Coluracetam ndi yopanda poizoni ndipo imadziwika kuti imalekerera komanso ndi yotetezeka.

 

Coluracetam powder Zogulitsa(Kumene Mungagule ufa wa Coluracetam wochuluka)

Kampani yathu imakhala ndiubwenzi wamtundu wautali ndi makasitomala athu chifukwa timayang'ana kwambiri ntchito yamakasitomala komanso kupereka zopambana. Ngati muli ndi chidwi ndi malonda athu, timasinthasintha makonda anu kuti agwirizane ndi zosowa zanu ndipo nthawi yathu yotsogoza mwachangu imatsimikizira kuti mudzalawa malonda athu nthawi. Timayang'ananso ntchito zowonjezera phindu. Tili ndi mafunso azithandizo ndi chidziwitso chothandizira bizinesi yanu.

Ndife akatswiri othandizira ufa wa Coluracetam kwazaka zingapo, timagulitsa zinthu ndi mtengo wampikisano, ndipo malonda athu ndiabwino kwambiri ndipo amayesedwa okhwima, odziyimira pawokha kuti awonetsetse kuti ndiwotetezeka padziko lonse lapansi.

 

Zothandizira

[1] Akaike A, et al. (1998). Zoteteza za MKC-231, buku lapamwamba kwambiri logine limakulitsa chowonjezera, pa glutamate cytotoxicity m'mitsempha yotukuka yotukuka. Jpn J Pharmacol.

[2] Bessho, T., Takashina, K., Tabata, R., Ohshima, C., Chaki, H., Yamabe, H., Egawa, M., Tobe, A., & Saito, K. (1996). Zotsatira zakuyandikira kwakukulu kwa choline kutengera zowonjezera 2- (2-oxopyrrolidin-1-yl) -N- (2,3-dimethyl-5,6,7,8-tetrahydrofuro [2,3-b] quinolin-4- yl) acetoamide pakuchepa kwa njira yophunzirira makoswe. Arzneimittel-Forschung, 46 (4), 369-373.

[3] Murai, S., Saito, H., Abe, E., Masuda, Y., Odashima, J., & Itoh, T. (1994). MKC-231, choline uptake enhancer, imathandizira kuchepa kwa kukumbukira kukumbukira ndikuchepetsa hippocampal acetylcholine yoyambitsidwa ndi ethylcholine aziridinium ion mu mbewa. Journal of Neural Transmission, 98 (1), 1–13 / bf10.1007 (Adasankhidwa) (Cross Ref)

[4] Takashina K, Bessho T, Mori R, Eguchi J, Saito K. MKC-231, choline cholimbikitsa: (2) Zotsatira pa kaphatikizidwe ndi kutulutsidwa kwa acetylcholine mu makoswe othandizidwa ndi AF64A. J Neural Transm (Vienna). 2008 Jul; 115 (7): 1027-35. doi: 10.1007 / s00702-008-0048-1. PubMed PMID: 18446264.

[5] Shirayama Y, Yamamoto A, Nishimura T, Katayama S, Kawahara R. Kudziwitsidwa kwaposachedwa kwa choline kukweza kupititsa patsogolo MKC-231 kumatsutsana ndi kufooka kwa chikhalidwe cha phencyclidine komanso kuchepetsa ma septal cholinergic neurons mu makoswe. Eur Neuropsychopharmacol. 2007 Sep; 17 (9): 616-26. PubMed PMID: 17467960.