Citicoline Sodium (33818-15-4)

Mwina 8, 2021

Cofttek ndiye wopanga ufa wabwino kwambiri wa Citicoline Sodium (CDP Choline Sodium) ku China. Fakitale yathu ili ndi dongosolo lathunthu loyang'anira kupanga (ISO9001 & ISO14001), lomwe limatha kupanga 220kg pamwezi.

 


Chikhalidwe: Mu Kupanga Misa
Unit: 1kg / thumba, 25kg / Drum

Citicoline Sodium (CDP Choline Sodium)(33818-15-4) Szizindikiro

Name: Citicoline Sodium (CDP Choline Sodium)
CAS: 33818-15-4
Chiyeretso 98%
Maselo chilinganizo: C14H25N4NaO11P2
Kulemera kwa Maselo: 510.308 g / mol
Melt Point: > 240 ° C
Dzina la mankhwala: Sodium Citicoline; Cdp-choline sodium
Mafanowo: Sodium [[(2S,3R,4S,5S)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]2-(trimethylazaniumyl)ethyl phosphate
InChI Key: YWAFNFGRBBBDDD-KDVMHAGBSA-M
Theka lamoyo: Maola 56
Kutupa: Mafuta mu DMSO, Madzi (Pang'onopang'ono)
Zosunga: Youma, mdima ndi 0 - 4 C kwakanthawi kochepa (masiku mpaka masabata) kapena -20 C kwakanthawi (miyezi mpaka zaka).
ntchito: Citicoline Sodium ndi wothandizira ma neuroprotective othandizira komanso wothandizira pazakudya
Maonekedwe: White wolimba powder

 

Sodium Citicoline (33818-15-4) Makina a NMR

Citicoline Sodium (33818-15-4) NMR Spectrum

Ngati mukufuna COA, MSDS, HNMR pagulu lililonse lazogulitsa ndi zina, chonde lemberani oyang'anira malonda.

 

Kodi Citicoline Sodium (CDP Choline Sodium)(33818-15-4) ?

Citicoline Sodium (CDP-choline Sodium, cytidine 5'-diphosphocholine) ufa ndimadzi osungunuka m'madzi omwe amatsogolera choline ndi cytidine mkati mwaubongo (womwe pambuyo pake umasintha kukhala uridine). Kwa anthu, Citicoline Sodium ndichinthu chofunikira kwambiri pothandiza kuti muchepetse ziwopsezo zoperewera m'mitsempha, matenda a chiwindi, ndi matenda ena. CDP-choline Sodium ndi imodzi mwazinthu zitatu zomwe zili ndi phospholipids yomwe imatha kuthandizidwa pakamwa (enawo ndi alpha-GPC ndi phosphatidylcholine).

 

Citicoline Sodium (CDP Choline Sodium)(33818-15-4) ubwino

CDP-choline imayambitsa biosynthesis ya kapangidwe kake ka phospholipids m'matumbo am'mitsempha, kumawonjezera kuchepa kwa ubongo ndikuchita magawo osiyanasiyana amitsempha yamagazi. Chifukwa chake, zatsimikiziridwa poyesa kuti CDP-choline imakulitsa magulu a noradrenaline ndi dopamine mu CNS.

Zowonjezerapozi zimagwiritsidwa ntchito poletsa kapena kuchepetsa kukhumudwa kukumbukira ku ukalamba chifukwa chakuti mamolekyu onsewo amapereka njira zothandizira anthu kuti azitha kuphunzira. Ngakhale kuti ikuwoneka bwino kwambiri kuposa phosphatidylcholine (PC) pambali imeneyi, mbali imodzi chifukwa cha kuwonjezereka kwa PC mu ubongo, potency yake ndi yofanana ndi ya Alpha-GPC.

 

Citicoline Sodium (CDP Choline Sodium)(33818-15-4) ntchito

CDP-choline ili ndi zina zomwe zingagwiritsidwe ntchito pokhudzana ndi kuzindikira. Amagwiritsidwa ntchito mobwerezabwereza monga kukumbukira kukumbukira unyamata, koma ngakhale kafukufuku wina wamatsenga akuwonetsa kuti izi ndizotheka pakamwa pa CDP-choline, palibe maphunziro aumunthu achichepere panthawiyi. Kafukufuku wina adawonetsa kuwonjezeka kwa chidwi ndi CDP-choline yochepa (yomwe imafunikira kutengeka), ndipo CDP-choline itha kukhala ndi gawo lodana ndi mankhwala osokoneza bongo motsutsana ndi cocaine komanso (umboni woyambirira ukuwonetsanso) chakudya nawonso ..

 

Citicoline Sodium (CDP Choline Sodium)(33818-15-4) ntchito

Citicoline Sodium (CDP Choline Sodium) ufa ndi mankhwala oletsa kutsekemera. Imachita polimbikitsa kulumikizana kwama foni, kulimbikitsa kaphatikizidwe ka SAMe, ndikuwonjezera kagayidwe kabwino ka shuga. Citicoline Sodium (CDP Choline Sodium) ufa ndi nucleotide mwachilengedwe; wapakatikati panjira yayikulu ya lecitin biosynthesis. Kuteteza mtima. Amagwiritsidwa ntchito pochiza matenda amisala komanso kupwetekedwa mutu. Mankhwala osokoneza bongo. Citicholine imawonetsa zoteteza mu ubongo ischemia, kuvulala koopsa muubongo, komanso kusokonezeka kwa kukumbukira. Posachedwapa anawonetsa mphamvu pothana ndi dementia akapatsidwa ndi AchEIs (Acetylcholinesterase inhibitor). Zimayimira zochitika za Neuroprotective, acnticonvulsant ndi sedative pamlingo wa 150mg / kg mu makoswe. Adawonetsedwa kutetezedwa ndi zotayidwa zomwe zimapangitsa chidwi chazidziwitso mu makoswe omwe amachepetsa kuchuluka kwa glutamate, kupsyinjika kwa okosijeni komanso KUSAKHALA kopitilira muyeso mu hippocampus.

 

Citicoline Sodium (CDP Choline Sodium)(33818-15-4) ufa Zogulitsa

(Komwe Mungagule Citicoline Sodium (CDP Choline Sodium)(33818-15-4) ufa wochuluka)

Kampani yathu imakhala ndiubwenzi wamtundu wautali ndi makasitomala athu chifukwa timayang'ana kwambiri ntchito yamakasitomala komanso kupereka zopambana. Ngati muli ndi chidwi ndi malonda athu, timasinthasintha makonda anu kuti agwirizane ndi zosowa zanu ndipo nthawi yathu yotsogoza mwachangu imatsimikizira kuti mudzalawa malonda athu nthawi. Timayang'ananso ntchito zowonjezera phindu. Tili ndi mafunso azithandizo ndi chidziwitso chothandizira bizinesi yanu.

Ndife akatswiri Citicoline Sodium (CDP Choline Sodium)(33818-15-4) wogulitsa ufa kwa zaka zingapo, timagulitsa zinthu ndi mtengo wopikisana, ndipo malonda athu ndiabwino kwambiri ndipo amayesedwa mosamalitsa, odziyimira pawokha kuti awonetsetse kuti ndi kotheka kugwiritsidwa ntchito padziko lonse lapansi.

 

Zothandizira

[1] Tyurenkov IN, Kurkin DV, Bakulin DA, Volotova EV, Chafeev MA. [Cerebroprotective shughuli za metformin, gosogliptin, citicoline ndi buku la GPR119 agonist mu ubongo ischemia pansi pa kuyesa kwa matenda a shuga mellitus]. Zh Nevrol Psikhiatr Im SS Korsakova. 2017; 117 (12. Vyp. 2): 53-59. doi: 10.17116 / jnevro201711712253-59. Russian. PubMed PMID: 29411746.

[2] Jiang JJ, Xie YM, Zhang Y, Zhang YK, Wang ZM, Han B. [Zithandizo zamankhwala zamankhwala za jakisoni wa Shuxuening pochiza kafukufuku wokhudzana ndi matenda amzere]. Zhongguo Zhong Yao Za Zhi. 2016 Dec; 41 (24): 4516-4520. doi: 10.4268 / cjcmm20162407. Wachichaina. PubMed PMID: 28936832.

[3] Liu Y, Wang J, Xu C, Chen Y, Yang J, Liu D, Niu H, Jiang Y, Yang S, Ying H. Othandizira opanga ma CD angapo-othandizira opanga ma CDP-choline oyendetsedwa ndi module wopereka kwa ATP. Pulogalamu Microbiol Biotechnol. 2017 Feb; 101 (4): 1409-1417. doi: 10.1007 / s00253-016-7874-0. Epub 2016 Oct 13. PubMed PMID: 27738720.

[4] Giménez R, Raïch J, Aguilar J (Novembala 1991). "Zosintha mu ubongo striatum dopamine ndi acetylcholine receptors chifukwa cha CDP-choline chithandizo cha mbewa zokalamba". British Journal ya Mankhwala. 104 (3): 575-8. onetsani: 1111 / j.1476-5381.1991.tb12471.x. PMC1908237PMID1839138.

[5] Tardner, P. (2020-08-30). "Kugwiritsa ntchito citicoline pochiza kuchepa kwazindikiritso komanso kuwonongeka kwazindikiritso: Kusanthula meta zolemba zamankhwala • International Journal of Environmental Science & Technology". International Journal of Environmental Science & Technology. Kubwezeretsedwa 2020-08-31.