GABA ufa (56-12-2)

Mwina 19, 2021

Cofttek ndiye wopanga ufa wabwino kwambiri wa Gamma-aminobutyric acid (GABA) ku China. Fakitale yathu ili ndi dongosolo lathunthu loyang'anira kupanga (ISO9001 & ISO14001), lomwe limatha kupanga 260kg pamwezi.


Chikhalidwe: Mu Kupanga Misa
Unit: 1kg / thumba, 25kg / Drum

Szizindikiro

Name: Gamma-aminobutyric acid (GABA)
CAS: 56-12-2
Chiyeretso 98%
Maselo chilinganizo: C4H9NO2
Kulemera kwa Maselo: 103.120 g / mol
Melt Point: 203.7 ° C
Dzina la mankhwala: 4-aminobutanoic acid
Mafanowo: 4-Aminobutanoic acid

gamma-aminobutyric acid

GABA

InChI Key: BTCSSZJGUNDROE-UHFFFAOYSA-N
Theka lamoyo: N / A
Kutupa: Kusungunuka m'madzi (130 g / 100 mL)
Zosunga: 0 - 4 C kwakanthawi kochepa (masiku mpaka masabata), kapena -20 C kwakanthawi (miyezi)
ntchito: GABA imawerengedwa kuti ndi yoteteza ma neurotransmitter chifukwa imatchinga, kapena imalepheretsa, kuwonetsa maubongo ena ndikuchepetsa zochitika mumanjenje anu.
Maonekedwe: ufa woyera wa microcrystalline

 

Gamma-aminobutyric acid (GABA) (56-12-2) Makina a NMR

Gamma-aminobutyric acid (GABA) (56-12-2) NMR Spectrum

Ngati mukufuna COA, MSDS, HNMR pagulu lililonse lazogulitsa ndi zina, chonde lemberani oyang'anira malonda.

 

Kodi Gamma-aminobutyric acid ndi chiyani?

Gamma aminobutyric acid (GABA) ndi amino acid mwachilengedwe womwe umagwira ntchito ngati neurotransmitter muubongo wanu. Ma Neurotransmitters amagwira ntchito ngati amithenga amagetsi. GABA imawerengedwa kuti ndi yoteteza ma neurotransmitter chifukwa imatchinga, kapena imalepheretsa, kuwonetsa maubongo ena ndikuchepetsa zochitika mumanjenje anu.

Gamma-aminobutyric acid (GABA) ufa ndi neurotransmitter yodalirika yomwe imawongolera kukondweretsedwa kwa mitsempha, kamvekedwe ka minofu, kukula kwa maselo, kukula kwaubongo, komanso malingaliro. Pakukula, GABA imagwira ntchito yotulutsa ma neurotransmitter osangalatsa koma amasintha kenako nkuyamba kugwira ntchito yoletsa. GABA imawonetsa nkhawa, anticonvulsant, ndi zochitika zamankhwala, zomwe zimapangitsa kupumula komanso kuchepetsa nkhawa m'mankhwala. Udindo wake waukulu ndikuchepetsa kuchepa kwa mitsempha m'mitsempha yonse. GABA imagulitsidwa ngati chowonjezera pazakudya.

 

GABA (56-12-2) maubwino

GABA yogona

"GABA imathandiza kuti thupi ndi malingaliro zizitha kumasuka ndikugona tulo tofa nato usiku wonse," atero a Michael J. Breus, Ph.D., katswiri wazamisala wazachipatala komanso katswiri wodziwa kugona. Ma GABA-A receptors amadziwikanso kwambiri mu thalamus, dera laubongo lomwe limagwira nawo ntchito yogona, ndipo kafukufuku wina, odwala omwe ali ndi tulo anali ndi milingo ya GABA pafupifupi 30% yotsika kuposa anthu omwe alibe vuto la kugona.

Kafukufuku waposachedwa, omwe atenga nawo gawo omwe adatenga 100 mg ya GABA (PharmaGABA) asanagone adagona mwachangu ndipo adagona bwino atatha sabata limodzi lowonjezera.

"Thupi lanu likatulutsa [GABA], dongosolo lanu lamanjenje limachepetsa, zomwe zimapangitsa munthu kukhala womasuka, ndipo nthawi zambiri amagona. M'malo mwake, zinthu zambiri zothandizira kugona tulo zimathandizira kuchuluka kwa GABA muubongo, "akutero a Breus.

Kuphatikiza apo, supplementation ndi magnesium, yomwe ndi GABA agonist (mwachitsanzo, chinthu chomwe chimamangirira ma GABA receptors ndikuwayambitsa chimodzimodzi ndi GABA, akufotokozera Ruhoy), yawonetsedwa kuti imathandizira kugona bwino.

 

GABA wamavuto komanso malingaliro amantha

Popeza GABA amatenga gawo pothana ndi chisangalalo cha glutamine, amaganiza kuti zimathandizanso kuchepetsa nkhawa (ndichifukwa chake mankhwala ambiri olimbana ndi nkhawa amalimbana ndi ma GABA-A receptors). Kafukufuku angapo akuwonetsa momwe milingo yokwanira ya GABA imatha kuyambitsa mavuto.

Pakafukufuku kamodzi kakang'ono, ofufuza adatenga nawo gawo omwe amamwa madzi osungunuka, madzi osungunuka ndi L-theanine (chopumira cha tiyi wobiriwira), kapena madzi osungunuka omwe ali ndi GABA (PharmaGABA). Patatha mphindi makumi asanu ndi limodzi, adayesa mafunde awo aubongo ndi mayeso a electroencephalogram (EEG) ndipo adapeza kuti GABA idakulitsa kwambiri ma alpha brainwaves (omwe amapangidwa mosatekeseka) ndikuchepetsa ma brainwaves a beta (omwe amawoneka munthawi zovuta) poyerekeza ndi L -theanine kapena madzi.

Kuyesanso kwina kochitidwa ndi ofufuza omwewo, omwe akuchita nawo mantha akwezeka adalandila placebo kapena 200 mg GABA (mwa mtundu wa PharmaGABA) asadadutse mlatho woyimitsidwa pamwamba pa canyon. Magulu amtundu wa antibody immunoglobulin-A (sIgA) -omwe amaphatikizidwa ndi kupumula kwambiri - adayesedwa magawo angapo. Gulu la placebo lidakumana ndi kuchepa kwakukulu kwa sIgA, pomwe magulu a gulu la GABA adakhalabe olimba ndipo adakwera pang'ono pofika kumapeto, kuwonetsa kuti amakhala omasuka.

 

GABA ndi malingaliro

Kafukufuku akuwonetsa kuti GABA imatha kuthandiza munthu kuchita zinthu zamaganizidwe zomwe zimafunikira chidwi kwambiri ndikuthana ndi kutopa kwamaganizidwe ndi thupi komwe kumawononga kusungaku.

Phunziro limodzi laling'ono, omwe adatenga nawo gawo (angapo omwe anali ndi kutopa kwambiri) adapatsidwa chakumwa chokhala ndi 0, 25, kapena 50 mg wa GABA kenako adapemphedwa kuti achite zovuta zamasamu. Ofufuzawo adapeza kuti omwe ali m'magulu awiri a GABA adachepetsa kwambiri kutopa kwamaganizidwe ndi kuthupi, monga kumayeza ndi kuchepa kwa ma biomarker ena kuphatikiza cortisol. -kuthetsa.

 

GABA wamagazi wathanzi

Kafukufuku woyambirira akuwonetsa kuti GABA imatha kulimbikitsa kuthamanga kwa magazi, osachepera malinga ndi kafukufuku wina wapa labu. Amakhulupirira kuti GABA ikhoza kukhala ikuthandiza mitsempha yamagazi kuti ikule bwino, potero imalimbikitsa kuthamanga kwa magazi.

Kumvetsetsa momwe GABA ingathandizire kuthandizira kuthamanga kwa magazi kumafunikira kafukufuku wamphamvu, koma kafukufuku woyambirira adapeza kuti kuwonjezerapo tsiku lililonse ndi 80 mg ya GABA kumathandizira kuthamanga kwa magazi kwa achikulire.

 

Gamma-aminobutyric acid ntchito?

Gamma-aminobutyric acid, yomwe nthawi zambiri imadziwika kuti GABA, ndi amino acid komanso neurotransmitter, mtundu wa mankhwala omwe amayang'anira kunyamula zidziwitso kuchokera pa selo limodzi kupita ku linzake.

Wopangidwa mwachilengedwe mthupi, GABA imapezekanso mu mawonekedwe owonjezera. Opanga amati ma GABA othandizira amatha kuthandizira kukulitsa milingo ya GABA muubongo ndikuthandizira nkhawa, kupsinjika, kukhumudwa, komanso mavuto ogona. M'malo mwake, opanga ena othandizira GABA amatcha "mtundu wachilengedwe wa Valium" - mwina kutanthauza kuti amachepetsa kupsinjika ndikuwonjezera kupumula ndi kugona.

Kafukufuku akuwonetsa kuti GABA itha kutenga gawo lalikulu podziteteza ku kukhumudwa ndi nkhawa. Mwachitsanzo, kafukufuku wofalitsidwa mu Journal of Biological Chemistry mu 2010 akuwonetsa kuti anthu omwe ali ndi vuto lalikulu la kukhumudwa atha kukhala ndi mwayi wochepa wa GABA. Zotsatirazi zikugwirizana ndi kuti GABA ndiye njira yoyamba yochepetsera (inhibitory) neurotransmitter muubongo.

 

mlingo

GABA imamwedwa pakamwa kuti ichepetse nkhawa, kusintha malingaliro, kuchepetsa zizindikilo za premenstrual syndrome (PMS), komanso kusamalira vuto la kuchepa kwa matenda (ADHD). Amagwiritsidwanso ntchito popititsa patsogolo kukula kwa minofu, mafuta oyaka, kukhazikika kwa magazi, komanso kuchepetsa ululu.

Chifukwa pali zochepa pazokhudza zowonjezera za GABA, palibe mlingo wovomerezeka ngati mungafune kuwonjezera.

M'mayesero azachipatala, mitundu ingapo ya GABA zowonjezera zagwiritsidwa ntchito. Mwachitsanzo, 100 ml ya mkaka wofukiza wokhala ndi 10-12 mg ya GABA pa 100 mL imagwiritsidwa ntchito ndi odwala omwe ali ndi kuthamanga kwa magazi mu kafukufuku komwe amamwa chakumwa tsiku lililonse pachakudya cham'mawa kwa milungu 12. Pakafukufuku wina, chlorella chowonjezera chomwe chili ndi 20 mg ya GABA idatengedwa kawiri tsiku lililonse kwa milungu 12.

 

GABA ufa Zogulitsa(Kumene Mungagule GABA ufa wochuluka)

Kampani yathu imakhala ndiubwenzi wamtundu wautali ndi makasitomala athu chifukwa timayang'ana kwambiri ntchito yamakasitomala komanso kupereka zopambana. Ngati muli ndi chidwi ndi malonda athu, timasinthasintha makonda anu kuti agwirizane ndi zosowa zanu ndipo nthawi yathu yotsogoza mwachangu imatsimikizira kuti mudzalawa malonda athu nthawi. Timayang'ananso ntchito zowonjezera phindu. Tili ndi mafunso azithandizo ndi chidziwitso chothandizira bizinesi yanu.

Ndife akatswiri othandizira GABA ufa kwa zaka zingapo, timapereka zinthu ndi mtengo wopikisana, ndipo malonda athu ndiabwino kwambiri ndipo amayesedwa mozama, odziyimira pawokha kuti awonetsetse kuti ndi kotheka kugwiritsidwa ntchito padziko lonse lapansi.

 

Zothandizira

[1] Haynes, William M., mkonzi. (2016). CRC Handbook Chemistry ndi Fiziki (97th ed.). CRC Press. mas. 5-88. ISBN 978-1498754286.

[2] WG Van der Kloot; J. Robbins (1959). "Zotsatira za GABA ndi picrotoxin pamphamvu yolumikizana komanso kupindika kwa crayfish minofu". Zochitika. 15:36.

[3] Roth RJ, Cooper JR, Bloom FE (2003). Maziko Achilengedwe a Neuropharmacology. Oxford [Oxfordshire]: Oxford University Press. p. 106. ISBN 978-0-19-514008-8.