Alpha Lipoic Acid (ALA)

April 20, 2021

Cofttek ndiye wopanga ufa wabwino kwambiri wa Alpha Lipoic Acid (ALA) ku China. Fakitale yathu ili ndi makina athunthu opanga (ISO9001 & ISO14001), omwe amatha kupanga 1000kg pamwezi.

 


Chikhalidwe: Mu Kupanga Misa
Unit: 1kg / thumba, 25kg / Drum

Alpha Lipoic Acid (ALA) (1077-28-7) Szizindikiro

Name: Alpha Lipoic Acid (ALA)
CAS: 1077-28-7
Chiyeretso 98%
Maselo chilinganizo: C8H14O2S2
Kulemera kwa Maselo: 206.33 g / mol
Melt Point: 60-62 ° C (140-144 ° F; 333-335 K)
Dzina la mankhwala: (R) -5- (1,2-Dithiolan-3-yl) asidi pentanoic;

α-Lipoic asidi; Alpha lipoic asidi; Asidi Thioctic; 6,8-Dithiooctanoic acid

Mafanowo: (±) -α-Lipoic acid, (±) -1,2-Dithiolane-3-pentanoic acid, 6,8-Dithiooctanoic acid, DL -α-Lipoic acid, DL -6,8-Thioctic acid, Lip (S2 )
InChI Key: Opanga: AGBQKNBQESQNJD-UHFFFAOYSA-N
Theka lamoyo: Hafu ya moyo wa ALA woyankhulidwa pakamwa ndi mphindi 30 zokha
Kutupa: Osungunuka Kwambiri Mumadzi (0.24 g / L); Kusungunuka kwa ethanol 50 mg / mL
Zosunga: 0 - 4 C kwakanthawi kochepa (masiku mpaka masabata), kapena -20 C kwakanthawi (miyezi)
ntchito: Alpha-lipoic acid imagwiritsidwa ntchito m'thupi kupukusa chakudya komanso kupanga mphamvu ku ziwalo zina m'thupi. Alpha-lipoic acid imawoneka kuti imagwira ntchito ngati antioxidant, zomwe zikutanthauza kuti imatha kuteteza ubongo ukadzawonongeka kapena kuvulala.
Maonekedwe: Makristalu achikasu ngati singano

 

Alpha Lipoic Acid (ALA) (1077-28-7) Makina a NMR

 

Alpha Lipoic Acid (ALA) (1077-28-7) - NMR Spectrum

Ngati mukufuna COA, MSDS, HNMR pagulu lililonse lazogulitsa ndi zina, chonde lemberani oyang'anira malonda.

 

Alpha Lipoic Acid (ALA) (1077-28-7)?

Alpha-lipoic acid ndi gawo lomwe limapezeka mwachilengedwe mkati mwa khungu lililonse la thupi la munthu. Ntchito yake yayikulu ndikusintha shuga wamagazi (glucose) kukhala mphamvu pogwiritsa ntchito mpweya, njira yomwe imadziwika kuti metabolism ya aerobic. Alpha-lipoic acid imadziwikanso kuti antioxidant, kutanthauza kuti imatha kusokoneza mankhwala owopsa omwe amatchedwa ma radicals aulere omwe amawononga maselo amtundu wa chibadwa.

Chomwe chimapangitsa alpha-lipoic acid kukhala wapadera ndikuti imasungunuka m'madzi ndi mafuta. Izi zikutanthauza kuti imatha kupulumutsa mphamvu nthawi yomweyo kapena kuisunga kuti adzagwiritse ntchito mtsogolo.

Alpha-lipoic acid itha kugwiritsanso ntchito ma antioxidants "omwe amagwiritsidwa ntchito", kuphatikiza vitamini C, vitamini E, ndi mankhwala amino acid omwe amadziwika kuti glutathione.1 Nthawi zonse ma antioxidantswa akamachepetsa kusintha kwaulere, amasokoneza ndikukhala omasuka okha. Alpha-lipoic acid imathandizira kuwabwezeretsa pomwetsa ma elekitironi owonjezera ndikuwasintha kuti abwerere mawonekedwe awo okhazikika.

Alpha-lipoic acid nthawi zina amatengedwa ngati chowonjezera poganiza kuti chitha kupititsa patsogolo ntchito zina zamagetsi, kuphatikiza kuwotcha mafuta, kupanga collagen, komanso kuwongolera magazi m'magazi. Pali umboni wochulukirapo wazomwe akunenazi.

 

Alpha Lipoic Acid (ALA) (1077-28-7) maubwino

shuga

Zakhala zikuganiziridwa kale kuti alpha-lipoic acid imathandizira pakulamulira shuga powonjezera liwiro momwe shuga wamagazi amasinthira. Izi zitha kuthandizira kuchiza matenda ashuga, matenda omwe amadziwika ndi milingo yayitali kwambiri yamagazi.

Kuwunika mwadongosolo kwa 2018 ndikuwunika meta kwamayeso 20 omwe amayesedwa mosiyanasiyana a anthu omwe ali ndi vuto la kagayidwe kachakudya (ena anali ndi matenda amtundu wa 2, ena anali ndi zovuta zina zamagetsi) adapeza kuti lipoic acid supplementation imachepetsa kusala magazi m'magazi, insulin insulin, insulin kukana, ndi hemoglobin yamagazi Mulingo wa A1C.

 

Kupweteka kwa Mitsempha

Neuropathy ndi mawu azachipatala omwe amagwiritsidwa ntchito pofotokoza zowawa, dzanzi, komanso kumva zachilendo zomwe zimayambitsidwa ndi kuwonongeka kwa mitsempha. Nthawi zambiri, kuwonongeka kumayambitsidwa ndi kupsyinjika kwa oxidative komwe kumayikidwa pamitsempha ndi matenda osachiritsika monga matenda ashuga, matenda a Lyme, ma shingles, matenda a chithokomiro, impso kulephera, ndi HIV.

Ena amakhulupirira kuti alpha-lipoic acid, yomwe imaperekedwa mokwanira, ingathe kuthana ndi vutoli pogwiritsa ntchito mphamvu ya antioxidant. Pakhala pali umboni wazomwe zimachitika mwa anthu omwe ali ndi matenda ashuga, matenda omwe angafooketse anthu omwe ali ndi matenda ashuga.

Kafukufuku wochokera ku Netherlands ku 2012 adatsimikiza kuti kumwa mankhwala a alpha-lipoic acid operekedwa kwamasabata atatu kumachepetsa "kupweteka kwakanthawi kwamankhwala."

Mofanana ndi maphunziro am'mbuyomu a shuga, mankhwala am'mlomo a alpha-lipoic acid anali osagwira ntchito kwenikweni kapena anali opanda mphamvu konse.

 

kuwonda

Kutha kwa alpha-lipoic acid kukulitsa kuyaka kwa kalori ndikulimbikitsa kuchepa kwa thupi kwakokomezedwa ndi akatswiri ambiri azakudya ndi othandizira opanga. Ndikunenedwa kuti, pali umboni wochulukirapo wosonyeza kuti alpha-lipoic acid imatha kukopa kulemera, ngakhale modzichepetsa.

Kuwunikanso kwa 2017 kuchokera ku Yale University kunapeza kuti alpha-lipoic acid othandizira, kuyambira muyezo wa 300 mpaka 1,800 mg tsiku lililonse, adathandizira kuyambitsa kulemera kwapakati pa mapaundi a 2.8 poyerekeza ndi placebo.

Panalibe mgwirizano pakati pa alpha-lipoic supplement dose ndi kuchuluka kwa kuchepa thupi. Kuphatikiza apo, kutalika kwa chithandizo kumawoneka kuti kumakhudza kuchuluka kwa thupi la munthu (BMI), koma osati kulemera kwenikweni kwa munthuyo.

Izi zikutanthawuza kuti, ngakhale zikuwoneka kuti mutha kuchepa kwambiri ndi alpha-lipoic acid, thupi lanu limatha kusintha chifukwa mafuta amasinthidwa pang'onopang'ono ndi minofu yowonda.

 

mkulu mafuta

Alpha-lipoic acid yakhala ikukhulupiriridwa kuti imakhudza kulemera ndi thanzi posintha mawonekedwe a lipid (mafuta) m'magazi. Izi zimaphatikizapo kuwonjezera mafuta "abwino" apamwamba kwambiri a lipoprotein (HDL) cholesterol pomwe amachepetsa "zoipa" cholesterol-lipoprotein (LDL) cholesterol ndi triglycerides. Kafukufuku waposachedwa akuwonetsa kuti izi sizingakhale choncho.

Pakafukufuku waku 2011 wochokera ku Korea, akulu 180 adapereka 1,200 mpaka 1,800 mg ya alpha-lipoic acid idataya 21% kuposa kulemera kwa gulu la placebo pambuyo pa masabata 20 koma osasintha kalikonse mu cholesterol, LDL, HDL, kapena triglycerides.

M'malo mwake, kuchuluka kwa alpha-lipoic acid komwe kumawonjezera kuchuluka kwa cholesterol ndi LDL mwa omwe atenga nawo mbali phunziroli.

 

Khungu lowonongeka ndi dzuwa

Opanga zodzoladzola amakonda kudzitama kuti malonda awo amapindula ndi mankhwala a "anti-aging" a alpha-lipoic acid. Kafukufuku akuwonetsa kuti pakhoza kukhala kuti ena amakhulupirira izi. Nkhani yowunikiranso kuti ndi antioxidant yamphamvu ndipo yaphunziridwa chifukwa cha zoteteza zake kuwonongeka kwa radiation.

 

Alpha Lipoic Acid (ALA) (1077-28-7) ntchito?

Alpha-lipoic acid kapena ALA ndimapangidwe achilengedwe omwe amapangidwa mthupi. Imagwira ntchito zofunikira pama cellular, monga kupanga mphamvu. Malingana ngati muli wathanzi, thupi limatha kupanga ALA yonse yomwe imafunikira pazinthu izi. Ngakhale zili choncho, pakhala pali chidwi chambiri posachedwa chogwiritsa ntchito zowonjezera za ALA. Othandizira a ALA amadzinenera kuti amachokera pazothandiza pakuthana ndi matenda monga matenda ashuga ndi HIV kupititsa patsogolo kuonda.

 

Alpha Lipoic Acid (ALA) (1077-28-7) Mlingo

Ngakhale zimawoneka ngati zotetezeka, palibe malangizo owongolera kugwiritsa ntchito moyenera alpha-lipoic acid. Zowonjezera zam'kamwa zambiri zimagulitsidwa m'magulu kuyambira 100 mpaka 600 mg. Kutengera kuchuluka kwa maumboni apano, kuchuluka kwa tsiku ndi tsiku mpaka 1,800 mg kumayesedwa kuti ndi kotetezeka kwa akulu.

Ndikunenedwa kuti, chilichonse kuyambira kulemera kwa thupi ndi zaka mpaka chiwindi komanso magwiridwe antchito a impso zingakhudze zomwe zili zotetezeka kwa inu monga munthu aliyense. Monga lamulo la thupi, lolani mosamala ndipo nthawi zonse musankhe mankhwala ochepa.

Alpha lipoic acid amathandizira pa intaneti komanso m'masitolo ambiri azakudya ndi malo ogulitsa mankhwala. Kuti mukhale ndi mayamwidwe ochulukirapo, zowonjezera ziyenera kutengedwa m'mimba yopanda kanthu.

 

Alpha-lipoic Acid ufa Zogulitsa(Kumene Mungagule ufa wa Alpha-lipoic Acid wochuluka)

Kampani yathu imakhala ndiubwenzi wamtundu wautali ndi makasitomala athu chifukwa timayang'ana kwambiri ntchito yamakasitomala komanso kupereka zopambana. Ngati muli ndi chidwi ndi malonda athu, timasinthasintha makonda anu kuti agwirizane ndi zosowa zanu ndipo nthawi yathu yotsogoza mwachangu imatsimikizira kuti mudzalawa malonda athu nthawi. Timayang'ananso ntchito zowonjezera phindu. Tili ndi mafunso azithandizo ndi chidziwitso chothandizira bizinesi yanu.

Ndife akatswiri a Alpha-lipoic Acid powder ogulitsa kwa zaka zingapo, timagulitsa zinthu ndi mtengo wopikisana, ndipo malonda athu ndiabwino kwambiri ndipo amayesedwa mwamphamvu, odziyimira pawokha kuti awonetsetse kuti ndiwotheka kugwiritsa ntchito padziko lonse lapansi.

 

Zothandizira

  1. Mwinilunga, GRMM; Wopanda, A (1991). "Kuwombera asidi wa hypochlorous ndi lipoic acid". Biochemical Pharmacology. 42 (11): 2244-6. onetsani: 10.1016 / 0006-2952 (91) 90363-A. PMID 1659823.
  2. Biewenga, GP; Haenen, GR; Bast, A (Seputembara 1997). "Mankhwala a antioxidant lipoic acid". General Pharmacology. 29 (3): 315-31. onetsani: 10.1016 / S0306-3623 (96) 00474-0. PMID 9378235.
  3. Schupke, H; Hempel, R; Peter, G; Chidziwitso, R; et al. (Juni 2001). "Njira zatsopano zamagetsi za alpha-lipoic acid". Kugwiritsa Ntchito Mankhwala Osokoneza bongo ndi Kutaya. 29 (6): 855-62. PMID 11353754.
  4. Acker, DS; Wayne, WJ (1957). "Mwachangu komanso poizoni α-lipoic acid". Zolemba za American Chemical Society. 79 (24): 6483-6487. onetsani: 10.1021 / ja01581a033.
  5. Hornberger, CS; Wolemba Heitmiller, RF; Gunsalus, IC; Schnakenberg, GHF; et al. (1952). "Kupanga kukonzekera kwa lipoic acid". Zolemba za American Chemical Society. 74 (9): 2382. onetsani: 10.1021 / ja01129a511.