Vinpocetine ufa wabwino kwambiri (42971-09-5) Wopanga

Vinpocetine ufa

November 5, 2020

Cofttek ndiye wopanga wabwino kwambiri wa Vinpocetine ku China. Fakitale yathu ili ndi dongosolo lathunthu loyang'anira kupanga (ISO9001 & ISO14001), lomwe limapanga 340kg pamwezi.

Chikhalidwe: Mu Kupanga Misa
Unit: 1kg / thumba, 25kg / Drum

Vinpocetine ufa Szizindikiro

Name: Vinpocetine
CAS: 42971-09-5
Chiyeretso 98%
Maselo chilinganizo: C22H26N2O2
Kulemera kwa Maselo: 350.454 g / mol
Melt Point: 147-149 ° C
Dzina la mankhwala: AY-27255, Cavinton, Eburnamenine-14-carboxylic acid, Ethyl Apovincaminate, Ethylapovincaminoate,
Mafanowo: Ethyl Ester, RGH-4405, TCV-3b, Vinpocetin, Vinpocetina, Vinpocétine.
InChI Key: Gawo #: DDNCQMVWWZOMLN-IRLDBZIGSA-N
Kuchotsa Gawo Lamoyo: 2.54 +/- 0.48 maola
Kutupa: Soluble ku DMSO, Methanol, Madzi
Zosunga: 0 - 4 C kwakanthawi kochepa (masiku mpaka masabata), kapena -20 C kwakanthawi (miyezi)
ntchito: Vinpocetine ndichida chochokera ku chomera cha Periwinkle chomwe chimagwiritsidwa ntchito ngati chodzitchinjiriza komanso chothandizira kulimbana ndi ukalamba. Chimodzi mwazofala kwambiri za nootropics, Vinpocetine itha kupititsa patsogolo kuthamanga kwa magazi ndipo imawonjezera kukumbukira; izi zakumapeto sizinafufuzidwe.
Maonekedwe: White powder

 

Vinpocetine (42971-09-5) Makina a NMR

Vinpocetine (42971-09-5) - NMR Spectrum

Ngati mukufuna COA, MSDS, HNMR pagulu lililonse lazogulitsa ndi zina, chonde lemberani oyang'anira malonda.

 

Kodi Vinpocetine (42971-09-5) ndi chiyani?

Vinpocetine ndi mankhwala a alkaloid omwe amachokera ku chomera cha periwinkle (makamaka, chopangidwa kuchokera ku molekyulu yotchedwa 'vincamine') yomwe imawoneka kuti ili ndi mbiri yogwiritsa ntchito m'maiko aku Europe pochiza kuchepa kwa chidziwitso, kuchira kwa stroke, ndi khunyu. Vinpocetine imagwiritsidwanso ntchito ngati nootropic popanga kuti ingalimbikitse kukumbukira kukumbukira.

 

Vinpocetine powder (42971-09-5) amapindula

Vinpocetine siyimitsidwa kwathunthu, koma zomwe zimayikidwa m'mapazi am'magazi mwachangu komanso mosavuta zimalowa muubongo momwe zimatha kugwira ntchito zake. Katundu yemwe amawoneka kuti amagwiritsidwa ntchito pakamwa vinpocetine supplementation amaphatikizira njira yoteteza ku poizoni (motsutsana ndi poizoni komanso kukondoweza mopitilira muyeso) ndikuchepetsa kutupa kwa mitsempha, pomwe mphamvu yakuzindikira sikuwoneka kuti ikuthandizidwa ndi umboni pakadali pano. Ngakhale vinpocetine ikuwoneka ngati yothandiza popewa poizoni kapena zopanikiza kuti zisayambitse amnesia, sichinawonetsedwe kuti chimapangitsa kukumbukira kukumbukira.

Vinpocetine imawonekeranso kuti ili ndi mphamvu pothana ndi kuchepa kwazidziwitso, koma kuchuluka kwa zolemba pamutuwu ndizocheperako kuposa mankhwala ena omwe amayesedwa chifukwa ichi (CDP-Choline kapena Alpha-GPC makamaka). Kafukufuku m'modzi wawona kusintha kwakanthawi kanthawi kogwiritsa ntchito piritsi la viniga ya 40mg, yomwe itha kukhala imodzi mwazosintha zofunikira kwa anthu athanzi pakadali pano.

Kulowetsedwa kwa vinpocetine kumawoneka kuti kumathandizira kuthamanga kwa magazi kupita muubongo osasintha mwachilengedwe, ndipo izi zimaganiziridwa (koma osawonetsedwa) kuti zizigwiritsidwa ntchito pakulowetsa mkamwa. Izi zitha kuchepetsa kupweteka kwa mutu komwe kumachitika chifukwa chapanikizika kwambiri, ndipo zikugwirizana ndi kagwiritsidwe ntchito ka mbewu ya periwinkle (kuchepetsa kupweteka kwa mutu).

 

Vinpocetine (42971-09-5) ntchito?

Njira zopangira vinpocetine ndizambiri. Zikuwoneka kuti zimalumikizana ndi njira zingapo za ion (sodium, potaziyamu, ndi calcium) pomwe zimayambitsa mavuto pakumasulidwa kwa ma neurotransmitter ndi neuroprotection pomwe dopamine kapena glutamate imaponderezedwa (ziwirizi, zikalimbikitsidwa ndi poizoni, zimatha kuyambitsa kuwonongeka kwa okosijeni). Imalumikizananso ndi alpha adrenergic receptors ndi TPSO receptor, ndipo ngakhale phindu lenileni la kulumikizana ndi ma receptor silikudziwika kuti mwina ndiwofunikira chifukwa limachitika pamayendedwe ofanana ndi momwe mayanjidwe ama ion amathandizira.

Vinpocetine imakhalanso PDE1 inhibitor, yomwe ndi njira yomwe imathandizira kuteteza mtima komanso kuzindikira. Tsoka ilo, kuletsa uku kumachitika pamlingo wokulirapo ndipo sikungagwire ntchito pamlingo wowonjezera wa vinpocetine.

Mofananamo ndi PDE1, mphamvu ya antidopaminergic ya vinpocetine komanso kuletsa mwachindunji ma glutaminergic receptors zonse zimawoneka kuti zimachitika kwambiri mu vitro ndipo sizingakhale zofunikira pakuwonjezera.

 

Vinpocetine (42971-09-5) Mlingo

Vinpocetine amatengedwa pamlingo wapa 15-60mg tsiku lililonse, wogawika magawo atatu tsiku lililonse ndi chakudya. Mlingo wotsika kwambiri ndi 5mg pa chilichonse mwazakudya zitatuzi, pomwe 20mg pachakudya chilichonse imawoneka kuti ndiyabwino kwambiri. Mlingo uwu umatengedwa kuti ungateteze ubongo, kupititsa patsogolo kuthamanga kwa magazi, ndikuchepetsa kuchepa kwa kuzindikira.

Mlingo kumapeto kwake kwamtunduwu (30-45mg Mlingo woyenera) utha kukhala wothandiza polimbikitsa kuzindikira ndi kukumbukira kukumbukira kwa anthu athanzi, koma palibe umboni wambiri womwe ukuwona izi.

Chenjezo: kwa amayi apakati, miyezo yofanana ya 10 mg / d yakhala ikugwirizanitsidwa ndi poizoni wa fetus m'maphunziro a nyama. 10 mg / d itha kukhalanso yowopsa, makamaka mukamatenga nthawi yonse yolera.

 

Vinpocetine ufa Zogulitsa(Kumene Mungagule Vinpocetine ufa wochuluka)

Kampani yathu imakhala ndiubwenzi wamtundu wautali ndi makasitomala athu chifukwa timayang'ana kwambiri ntchito yamakasitomala komanso kupereka zopambana. Ngati muli ndi chidwi ndi malonda athu, timasinthasintha makonda anu kuti agwirizane ndi zosowa zanu ndipo nthawi yathu yotsogoza mwachangu imatsimikizira kuti mudzalawa malonda athu nthawi. Timayang'ananso ntchito zowonjezera phindu. Tili ndi mafunso azithandizo ndi chidziwitso chothandizira bizinesi yanu.

Ndife akatswiri opangira ufa wa Vinpocetine kwazaka zingapo, timagulitsa zinthu ndi mtengo wampikisano, ndipo malonda athu ndiabwino kwambiri ndipo amayesedwa mwamphamvu, odziyimira pawokha kuti awonetsetse kuti ndiwotheka kugwiritsa ntchito padziko lonse lapansi.

 

Zothandizira
  1. Abdel-Salam OME. Vinpocetine ndi piracetam zimayesetsa kupewetsa matenda opatsirana pogwiritsa ntchito mbewa. Pharmacol Rep. 2006; 58 (5): 680-691.17085860
  2. Akopov SE, Gabrielian ES. Zotsatira za aspirin, dipyridamole, nifedipine ndi Cavinton zomwe zimagwiritsa ntchito kuphatikizika kwa ma platelet opangidwa ndi magulu osiyanasiyana ophatikizira okha komanso kuphatikiza. Eur J Chipatala. 1992; 42 (3): 257-259.1577042
  3. Alkuraishy HM, Al-Gareeb AI, Albuhadilly AK. Vinpocetine ndi pyritinol: njira yatsopano yosinthira magazi m'matenda am'magazi am'magazi-kafukufuku wamankhwala wokhazikika. Zotsalira Res Int. 2014; 2014: 324307.25548768.

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